Department of Psychiatry, Chungnam National University Hospital, Daejeon, Republic of Korea.
Department of Psychiatry, National Medical Center, Seoul, Republic of Korea.
Medicine (Baltimore). 2022 Jun 24;101(25):e29440. doi: 10.1097/MD.0000000000029440.
We explored factors related to health-related quality of life (HRQOL), including psychiatric symptoms and stigma related to Middle East respiratory syndrome coronavirus (MERS-CoV) infection, among MERS-CoV survivors during the recovery period.Sixty-three MERS-COV survivors were recruited from five hospitals for a cohort study, one year after their infection in 2015. The subjects' demographic information and medical conditions associated with MERS-CoV were recorded. HRQOL was evaluated using the Short Form-8 Health Survey (SF-8). Depression, post-traumatic stress symptoms, chronic fatigue, and perceived stigma were assessed using several questionnairesThe mean physical component summary (PCS) and mean mental component summary (MCS) of the SF-8 score were below 50 T (43.47 ± 9.60, 45.74 ± 10.18). Depression, chronic fatigue, posttraumatic stress symptoms and stigma were negatively correlated with the SF-8 PCS and MCS. Multivariate logistic regression analysis showed that the PCS was associated with stigma (OR 8.66, 95% CI 1.96-38.23), whereas MCS was associated with depression (OR 26.62, 95% CI 3.56-198.85).The estimated HRQOL of MERS-CoV survivors during recovery was poor and appeared to be associated with depression and MERS-related stigma.
我们探讨了与中东呼吸综合征冠状病毒(MERS-CoV)感染相关的健康相关生活质量(HRQOL)的相关因素,包括精神病症状和耻辱感,这些因素在 MERS-CoV 幸存者的恢复期内存在。在 2015 年感染 MERS-CoV 一年后,我们从五家医院招募了 63 名 MERS-COV 幸存者进行队列研究。记录了研究对象的人口统计学信息和与 MERS-CoV 相关的医疗状况。使用简短形式 8 健康调查(SF-8)评估 HRQOL。使用几个问卷评估抑郁,创伤后应激症状,慢性疲劳和感知耻辱感。SF-8 评分的平均身体成分综合评分(PCS)和平均心理成分综合评分(MCS)均低于 50T(43.47±9.60,45.74±10.18)。抑郁,慢性疲劳,创伤后应激症状和耻辱感与 SF-8 PCS 和 MCS 呈负相关。多元逻辑回归分析表明,PCS 与耻辱感有关(OR 8.66,95%CI 1.96-38.23),而 MCS 与抑郁有关(OR 26.62,95%CI 3.56-198.85)。恢复期内 MERS-CoV 幸存者的 HRQOL 估计值较差,并且似乎与抑郁和与 MERS 相关的耻辱感有关。