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恢复期中东呼吸综合征冠状病毒幸存者的健康相关生活质量与抑郁和污名之间的关联。

Associations of health-related quality of life with depression and stigma in MERS-CoV survivors during the recovery period.

机构信息

Department of Psychiatry, Chungnam National University Hospital, Daejeon, Republic of Korea.

Department of Psychiatry, National Medical Center, Seoul, Republic of Korea.

出版信息

Medicine (Baltimore). 2022 Jun 24;101(25):e29440. doi: 10.1097/MD.0000000000029440.

Abstract

We explored factors related to health-related quality of life (HRQOL), including psychiatric symptoms and stigma related to Middle East respiratory syndrome coronavirus (MERS-CoV) infection, among MERS-CoV survivors during the recovery period.Sixty-three MERS-COV survivors were recruited from five hospitals for a cohort study, one year after their infection in 2015. The subjects' demographic information and medical conditions associated with MERS-CoV were recorded. HRQOL was evaluated using the Short Form-8 Health Survey (SF-8). Depression, post-traumatic stress symptoms, chronic fatigue, and perceived stigma were assessed using several questionnairesThe mean physical component summary (PCS) and mean mental component summary (MCS) of the SF-8 score were below 50 T (43.47 ± 9.60, 45.74 ± 10.18). Depression, chronic fatigue, posttraumatic stress symptoms and stigma were negatively correlated with the SF-8 PCS and MCS. Multivariate logistic regression analysis showed that the PCS was associated with stigma (OR 8.66, 95% CI 1.96-38.23), whereas MCS was associated with depression (OR 26.62, 95% CI 3.56-198.85).The estimated HRQOL of MERS-CoV survivors during recovery was poor and appeared to be associated with depression and MERS-related stigma.

摘要

我们探讨了与中东呼吸综合征冠状病毒(MERS-CoV)感染相关的健康相关生活质量(HRQOL)的相关因素,包括精神病症状和耻辱感,这些因素在 MERS-CoV 幸存者的恢复期内存在。在 2015 年感染 MERS-CoV 一年后,我们从五家医院招募了 63 名 MERS-COV 幸存者进行队列研究。记录了研究对象的人口统计学信息和与 MERS-CoV 相关的医疗状况。使用简短形式 8 健康调查(SF-8)评估 HRQOL。使用几个问卷评估抑郁,创伤后应激症状,慢性疲劳和感知耻辱感。SF-8 评分的平均身体成分综合评分(PCS)和平均心理成分综合评分(MCS)均低于 50T(43.47±9.60,45.74±10.18)。抑郁,慢性疲劳,创伤后应激症状和耻辱感与 SF-8 PCS 和 MCS 呈负相关。多元逻辑回归分析表明,PCS 与耻辱感有关(OR 8.66,95%CI 1.96-38.23),而 MCS 与抑郁有关(OR 26.62,95%CI 3.56-198.85)。恢复期内 MERS-CoV 幸存者的 HRQOL 估计值较差,并且似乎与抑郁和与 MERS 相关的耻辱感有关。

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