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合并眼科和风湿病评估在有眼部受累的系统性自身免疫性疾病:墨西哥的一个三级参考中心。

Combined Ophthalmology and Rheumatology Evaluation in Systemic Autoimmune Diseases with Ocular Involvement: A Third Level Reference Center in Mexico.

机构信息

Inflammatory Eye Disease Clinic, Asociación Para Evitar la Ceguera en México, I.A.P, Mexico City, Mexico.

Community Service at Inflammatory Eye Disease Clinic, Asociación Para Evitar la Ceguera en México, I.A.P, Mexico City, Mexico.

出版信息

Ocul Immunol Inflamm. 2023 Jul;31(5):989-995. doi: 10.1080/09273948.2022.2079532. Epub 2022 Jun 27.

DOI:10.1080/09273948.2022.2079532
PMID:35759649
Abstract

AIM

A cross-sectional descriptive study to determine the frequency of ocular manifestations associated with systemic autoimmune diseases in a third-level hospital in Mexico.

METHODS

Records from 2014 to 2017 at the Inflammatory Eye Disease Clinic of the Asociación Para Evitar la Cegueraen México were examined by both an ophthalmologist and a rheumatologist on the same day. Diagnosis was achieved from initial ocular manifestations with later systemic assessment.

RESULTS

Out of 311 medical records, 276 were included, 75% of the patients were female. Keratoconjunctivitis sicca was the most frequent ocular manifestation (33.3%), followed by anterior uveitis (29.5%), scleritis (23.2%), and peripheral ulcerative keratitis (7.2%). The leading autoimmune diseases were spondyloarthritis (29%), rheumatoid arthritis (28.6%), primary Sjögren's syndrome (10.5%) and granulomatosis with polyangiitis (9.1%). 41.3% of systemic disease diagnoses were made after an initial ocular manifestation.

CONCLUSIONS

Inflammatory eye manifestations can imply systemic autoimmune diseases. It is crucial to suspect and confirm this association and provide timely interdisciplinary management.

摘要

目的

一项横断面描述性研究,旨在确定在墨西哥一家三级医院中与系统性自身免疫性疾病相关的眼部表现的频率。

方法

对 2014 年至 2017 年在墨西哥预防失明协会炎症性眼病诊所的记录进行了检查,由眼科医生和风湿病学家在同一天进行。通过初始眼部表现和随后的系统评估来做出诊断。

结果

在 311 份病历中,有 276 份被纳入研究,75%的患者为女性。干燥性角结膜炎是最常见的眼部表现(33.3%),其次是前葡萄膜炎(29.5%)、巩膜炎(23.2%)和周边溃疡性角膜炎(7.2%)。主要的自身免疫性疾病是脊柱关节炎(29%)、类风湿关节炎(28.6%)、原发性干燥综合征(10.5%)和肉芽肿性多血管炎(9.1%)。41.3%的系统性疾病诊断是在最初的眼部表现后做出的。

结论

炎症性眼部表现可能提示系统性自身免疫性疾病。怀疑和确认这种关联并提供及时的跨学科管理至关重要。

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Ocul Immunol Inflamm. 2023 Jul;31(5):989-995. doi: 10.1080/09273948.2022.2079532. Epub 2022 Jun 27.
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