Bülow J, Jelnes R, Astrup A, Madsen J, Vilmann P
Scand J Clin Lab Invest. 1987 Feb;47(1):1-3. doi: 10.1080/00365518709168861.
Tissue/blood partition coefficients (lambda) for xenon were calculated for subcutaneous adipose tissue from the abdominal wall and the thigh, and for the perirenal adipose tissue after chemical analysis of the tissues for lipid, water and protein content. The lambda in the perirenal tissue was found to correlate linearly to the relative body weight (RBW) in per cent with the regression equation lambda = 0.045 . RBW + 0.99. The subcutaneous lambda on the abdomen correlated linearly to the local skinfold thickness (SFT) with the equation lambda = 0.22 SFT + 2.99. Similarly lambda on the thigh correlated to SFT with the equation lambda = 0.20 . SFT + 4.63. It is concluded that the previously accepted lambda value of 10 is generally too high in perirenal as well as in subcutaneous tissue. Thus, by application of the present regression equations, it is possible to obtain more exact estimates of the adipose tissue blood flow measured with the 133Xe wash-out method.
通过对腹壁和大腿的皮下脂肪组织以及肾周脂肪组织进行脂质、水和蛋白质含量的化学分析，计算出氙的组织/血液分配系数（λ）。肾周组织中的λ与相对体重（RBW）百分比呈线性相关，回归方程为λ = 0.045×RBW + 0.99。腹部皮下λ与局部皮褶厚度（SFT）呈线性相关，方程为λ = 0.22×SFT + 2.99。同样，大腿部的λ与SFT的相关方程为λ = 0.20×SFT + 4.63。得出的结论是，先前公认的λ值10在肾周组织和皮下组织中通常过高。因此，通过应用当前的回归方程，有可能更准确地估计用133Xe洗脱法测量的脂肪组织血流量。
