Department of Child Health, Dr. Sardjito Hospital/Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada, Yogyakarta, Indonesia.
Center for Child Health-Pediatric Research Office, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada, Yogyakarta, Indonesia.
BMC Pediatr. 2022 Jun 27;22(1):369. doi: 10.1186/s12887-022-03404-0.
Screening of critical congenital heart disease (CCHD) using pulse oximetry is a routine procedure in many countries, but not in Indonesia. This study aimed to evaluate the feasibility of implementing CCHD screening with pulse oximetry for newborns in Yogyakarta, Indonesia.
A cross-sectional study was conducted at four hospitals in Yogyakarta, Indonesia. Newborns aged 24-48 hours who met the inclusion criteria were screened on the right hand and left or right foot using a pulse oximeter. Positive results were indicated by: either (1) SpO level < 90% in one extremity, (2) SpO level of 90-94% in both right hand and either foot on three measurements conducted 1 hour apart, or (3) a saturation difference > 3% between the upper and lower extremity on three measurements conducted 1 hour apart. Positive findings were confirmed by echocardiography.
Of 1452 newborns eligible for screening, 10 had positive results and were referred for echocardiographic evaluation. Of those, 8 (6 per 1000 live birth, 8/1452) had CCHD. Barriers found during screening processes were associated with hospital procedures, equipment, healthcare personnel, and condition of the newborn.
Pulse oximetry screening might be feasible to be implemented within the routine newborn care setting for CCHD in Indonesia. In order to successfully implement pulse oximetry screening to identify CCHD in Indonesia, the barriers will need to be addressed.
在许多国家,使用脉搏血氧仪筛查严重先天性心脏病(CCHD)是常规程序,但印度尼西亚并非如此。本研究旨在评估在印度尼西亚日惹实施脉搏血氧仪筛查新生儿 CCHD 的可行性。
在印度尼西亚日惹的四家医院进行了一项横断面研究。符合纳入标准的 24-48 小时龄新生儿在右手和左手或右脚使用脉搏血氧仪进行筛查。阳性结果的指征为:(1)一侧肢体 SpO 水平<90%,(2)三次 1 小时间隔测量中,右手和任一脚的 SpO 水平为 90-94%,或(3)三次 1 小时间隔测量中,上下肢饱和度差异>3%。阳性发现通过超声心动图确认。
在 1452 名符合筛查条件的新生儿中,有 10 名出现阳性结果并被转介进行超声心动图评估。其中,8 名(每 1000 例活产 6 例,8/1452)患有 CCHD。筛查过程中发现的障碍与医院程序、设备、医护人员和新生儿状况有关。
脉搏血氧仪筛查可能适用于印度尼西亚在常规新生儿护理环境中筛查 CCHD。为了成功在印度尼西亚实施脉搏血氧仪筛查以识别 CCHD,需要解决这些障碍。