Kluckow Martin
Department of Neonatal Medicine, Royal North Shore Hospital and University of Sydney, Sydney, NSW 2065, Australia;
Int J Neonatal Screen. 2018 Jan 11;4(1):4. doi: 10.3390/ijns4010004. eCollection 2018 Mar.
Pulse oximetry screening of the well newborn to assist in the diagnosis of critical congenital heart disease (CCHD) is increasingly being adopted. There are advantages to diagnosing CCHD prior to collapse, particularly if this occurs outside of the hospital setting. The current recommended approach links pulse oximetry screening with the assessment for CCHD. An alternative approach is to document the oxygen saturation as part of a routine set of vital signs in each newborn infant prior to discharge, delinking the measurement of oxygen saturation from assessment for CCHD. This approach, the way that many hospitals which contribute to the Australian New Zealand Neonatal Network (ANZNN) have introduced screening, has the potential benefits of decreasing parental anxiety and expectation, not requiring specific consent, changing the interpretation of false positives and therefore the timing of the test, and removing the pressure to perform an immediate echocardiogram if the test is positive. There are advantages of introducing a formal screening program, including the attainment of adequate funding and a universal approach, but the barriers noted above need to be dealt with and the process of acceptance by a national body as a screening test can take many years.
对健康新生儿进行脉搏血氧饱和度筛查以辅助诊断严重先天性心脏病(CCHD)的做法正越来越多地被采用。在患儿病情恶化之前诊断出CCHD有诸多益处,尤其是在院外发生这种情况时。目前推荐的方法是将脉搏血氧饱和度筛查与CCHD评估联系起来。另一种方法是在每个新生儿出院前将血氧饱和度记录为常规生命体征的一部分,使血氧饱和度测量与CCHD评估脱钩。澳大利亚新西兰新生儿网络(ANZNN)的许多成员医院采用的就是这种方法,它可能具有降低家长焦虑和期望、无需特殊同意、改变对假阳性结果的解读以及检测时机、如果检测呈阳性则消除立即进行超声心动图检查的压力等潜在益处。引入正式筛查项目有诸多优点,包括获得充足资金和采用通用方法,但上述障碍需要加以解决,而且被国家机构接受作为一项筛查测试的过程可能需要很多年。