Liu Yi-Chen, Su Yu-Te, Huang Chih-Kang, Tsai Yu-Chi, Chen Yeu-Chin, Li Peng-Fei
Division of Endocrinology and Metabolism, Department of Internal Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei 114, Taiwan, R.O.C.
Department of Emergency Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei 114, Taiwan, R.O.C.
Mol Clin Oncol. 2022 Jun 7;17(1):122. doi: 10.3892/mco.2022.2555. eCollection 2022 Jul.
The present report described the case of a 71-year-old man who was admitted to the emergency department with a 7-day history of progressive left flank pain and tarry stool. Bedside point-of-care ultrasound of the left kidney showed lobulated ill-defined hypoechoic foci in the perirenal spaces with mild hydronephrosis. Subsequent contrast-enhanced abdominal computed tomography revealed lobulated low-density lesions in the bilateral perirenal space and paraaortic space. The patient was subsequently admitted to the internal medicine department of the hospital. Renal and duodenal biopsies were arranged, and pathology reports were consistent with the findings of plasmablastic lymphoma (PBL). This unusual presentation of flank pain and tarry stool caused by recurrent PBL highlighted that genitourinary or gastrointestinal manifestations could occur in cases of PBL recurrence. The patient received intensive chemotherapy regimens comprising a combination of etoposide, prednisone, vincristine, cyclophosphamide and doxorubicin hydrochloride for aggressive non-Hodgkin's lymphoma to achieve a good response.
本报告描述了一名71岁男性的病例，该患者因进行性左侧腰痛和柏油样便7天而入住急诊科。左肾床旁即时超声显示肾周间隙有分叶状、边界不清的低回声灶，伴有轻度肾积水。随后的腹部增强计算机断层扫描显示双侧肾周间隙和主动脉旁间隙有分叶状低密度病变。该患者随后被收治入院至医院内科。安排了肾脏和十二指肠活检，病理报告与浆母细胞淋巴瘤（PBL）的结果一致。复发性PBL引起的这种不寻常的腰痛和柏油样便表现突出表明，PBL复发时可能出现泌尿生殖系统或胃肠道表现。该患者接受了包含依托泊苷、泼尼松、长春新碱、环磷酰胺和盐酸多柔比星的联合强化化疗方案，用于侵袭性非霍奇金淋巴瘤，取得了良好的反应。
