Kazemipoor Maryam, Vatanchian Mohammad Kazem, Jambarsang Sara, Owlia Fatemeh
Department of Endodontics, School of Dentistry, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Private Practice, Yazd, Iran.
Int J Dent. 2022 Jun 18;2022:3518817. doi: 10.1155/2022/3518817. eCollection 2022.
The prevalence of anemia has been reported high in the female population in Iran. Anemia can be asymptomatic or can present in a variety of symptoms, especially when serum Hb values decrease. The present study would assess dental pulp response to cold and EPT sensibility tests in anemic and healthy women.
One hundred twenty maxillary central incisors belonging to participants aged 18-58 years were included in this survey. 60 patients had anemia (Hb ≤ 12.5) with/without medication (30 in each group) and 60 women as controls had no anemia (Hb > 12.5) with/without medication (30 in each group). Electric and cold pulpal sensibility tests were performed for all teeth. Statistical analysis was performed with t-student, Chi-square test, and two-way ANOVA. The significance level was set as < 0.05.
According to the results of this study, the mean value of hemoglobin in anemic and healthy women was 11.5 and 14.08 g/dl, respectively. The mean value of response to EPT in anemic women with and without medication was 3.21 and 3.14, respectively. The mean value of response to EPT in healthy women with and without medication was 3.81 and 3.58 g/dl, respectively. The mean value of time delay response to cold test was 3.03 and 2.82 s in anemic patients with/without medication. Also, the mean value of time delay response to cold test was 2.80 and 2.93 s in healthy women with/without medication. The pulpal responses to EPT tests had significant differences between anemic and healthy women (=0.043). There were no significant differences between anemic and healthy women considering time delay response to the cold test (=0.077).
Based on the results of the present study, tooth response to the EPT sensibility test may alter in anemic patients despite medication. The evidence from this preliminary study suggests that peripheral neuropathy in anemic patients could affect pulpal sensibility tests.
据报道，伊朗女性人群中贫血的患病率较高。贫血可能无症状，也可能表现为多种症状，尤其是当血清血红蛋白值下降时。本研究将评估贫血和健康女性牙髓对冷刺激和牙髓电活力测试（EPT）的反应。
本调查纳入了120颗属于18 - 58岁参与者的上颌中切牙。60例患者患有贫血（血红蛋白≤12.5），其中有/无用药情况各30例；60名作为对照的女性无贫血（血红蛋白>12.5），同样有/无用药情况各30例。对所有牙齿进行了电活力和冷刺激牙髓敏感性测试。采用t检验、卡方检验和双向方差分析进行统计分析。显著性水平设定为<0.05。
根据本研究结果，贫血和健康女性的血红蛋白平均值分别为11.5和14.08g/dl。有用药和无用药的贫血女性对EPT的反应平均值分别为3.21和3.14。有用药和无用药的健康女性对EPT的反应平均值分别为3.81和3.58g/dl。有用药和无用药的贫血患者对冷测试的延迟反应平均值分别为3.03和2.82秒。同样，有用药和无用药的健康女性对冷测试的延迟反应平均值分别为2.80和2.93秒。贫血和健康女性对EPT测试的牙髓反应存在显著差异（P = 0.043）。考虑到对冷测试的延迟反应，贫血和健康女性之间无显著差异（P = 0.077）。
基于本研究结果，贫血患者无论是否用药，牙齿对EPT敏感性测试的反应可能会改变。这项初步研究的证据表明，贫血患者的周围神经病变可能会影响牙髓敏感性测试。
