Sullivan J N, Salmon W D
South Med J. 1987 May;80(5):572-6. doi: 10.1097/00007611-198705000-00007.
We describe four cases of active pulmonary tuberculosis with hypercalcemia. The hypercalcemia developed three to eight weeks after the patients were admitted to the hospital, when clinical improvement due to specific drug therapy for the infection was also evident. The abnormality persisted for three to seven weeks and subsided spontaneously. In each case, the serum level of 1,25-dihydroxyvitamin D determined during the period of hypercalcemia (at the peak in three of the four cases) was low. This suggests that altered vitamin D metabolism is not the basis for hypercalcemia in all cases of pulmonary tuberculosis.
我们描述了4例伴有高钙血症的活动性肺结核病例。高钙血症在患者入院后3至8周出现，此时针对感染的特异性药物治疗也使临床症状明显改善。这种异常持续了3至7周后自行消退。在每例病例中，高钙血症期间（4例中有3例处于峰值）测定的血清1,25 - 二羟维生素D水平均较低。这表明维生素D代谢改变并非所有肺结核病例中高钙血症的病因。
