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60岁以下患者的单髁膝关节置换术可提供优异的临床疗效和10年植入物生存率:一项由ESSKA-欧洲膝关节协会早期骨关节炎小组进行的系统评价。

Unicompartmental knee arthroplasty in patients under the age of 60 years provides excellent clinical outcomes and 10-year implant survival: a systematic review : A study performed by the Early Osteoarthritis group of ESSKA-European Knee Associates section.

作者信息

Kyriakidis Theofylaktos, Asopa Vipin, Baums Mike, Verdonk René, Totlis Trifon

机构信息

Department of Orthopaedic Surgery and Traumatology, Erasme University Hospital, Université Libre de Bruxelles, Route de Lennik 808, 1070, Brussels, Belgium.

Sites South West London Elective Orthopaedic Centre, Epsom General Hospital, Dorking Road, Surrey, UK.

出版信息

Knee Surg Sports Traumatol Arthrosc. 2023 Mar;31(3):922-932. doi: 10.1007/s00167-022-07029-9. Epub 2022 Jun 28.

DOI:10.1007/s00167-022-07029-9
PMID:35763042
Abstract

PURPOSE

The purpose of the present study was to systematically review the clinical and functional outcomes following medial unicompartmental knee arthroplasty (UKA) in patients under the age of 60 years old.

METHODS

Using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, studies between 2012 and April 2022, on patients 18-60 years old who have had a unicompartmental knee replacement evaluating patient-reported outcomes measures (PROMs), were included. The Knee Society Scores (KSS) clinical score was considered the primary outcome. Pre- and post-operative range of motion (ROM), PROMs, complications and survival were recorded. Paired sample t testing was performed to compare the pre-operative with post-operative KSS.

RESULTS

Seventeen articles comprising 2083 unicompartmental arthroplasties were included. The follow-up range was between 1 and 15 years. In eligible studies, all reported outcomes were improved following UKA. The mean KSS clinical was significantly improved from 45.5 (SD: 9.6) pre-operatively to 89.4 (SD: 4.4) post-operatively (p = 0.0001). Mean implant survival ranged 86-96.5% at 10 years follow-up. There was no significant difference between mobile and fixed bearing in terms of ROM and KSS clinical. In total, 92 revisions and 7 re-operations with implant retention were reported.

CONCLUSION

Unicompartmental knee arthroplasty for medial osteoarthritis is a safe, reliable and effective treatment option for patients of 60 years or younger. It provides pain relief, satisfactory activity level, excellent clinical outcomes, and up to 96.5% implant survival at 10-year follow-up.

LEVEL OF EVIDENCE

IV.

摘要

目的

本研究旨在系统回顾60岁以下患者接受内侧单髁膝关节置换术(UKA)后的临床和功能结局。

方法

采用系统评价和Meta分析的首选报告项目指南,纳入2012年至2022年4月间关于18至60岁接受单髁膝关节置换术患者的研究,评估患者报告的结局指标(PROMs)。膝关节协会评分(KSS)临床评分被视为主要结局指标。记录术前和术后的活动范围(ROM)、PROMs、并发症和生存率。进行配对样本t检验以比较术前和术后的KSS。

结果

纳入了17篇文章,共2083例单髁关节置换术。随访时间为1至15年。在符合条件的研究中,所有报告的结局在UKA后均有所改善。KSS临床评分的平均值从术前的45.5(标准差:9.6)显著提高到术后的89.4(标准差:4.4)(p = 0.0001)。在10年随访时,平均植入物生存率为86%至96.5%。在ROM和KSS临床方面,活动型和固定型假体之间没有显著差异。总共报告了92次翻修和7次保留植入物的再次手术。

结论

对于60岁及以下的患者,内侧骨关节炎的单髁膝关节置换术是一种安全、可靠且有效的治疗选择。它能缓解疼痛,提供令人满意的活动水平,取得优异的临床结局,并且在10年随访时植入物生存率高达96.5%。

证据级别

IV级

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