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围产期 SARS-CoV-2 感染的传播和结局。

Perinatal Transmission and Outcomes of SARS-CoV-2 Infection.

机构信息

Department of Pediatrics, Dr S. N. Medical College, Jodhpur, Rajasthan, 342001, India.

Department of Microbiology, All India Institute of Medical Sciences, Jodhpur, Rajasthan, India.

出版信息

Indian J Pediatr. 2022 Nov;89(11):1123-1125. doi: 10.1007/s12098-022-04179-z. Epub 2022 Jun 28.

Abstract

Maternal SARS-CoV-2 infection can adversely affect the birth and neonatal outcomes. The authors prospectively enrolled 196 neonates born to 193 SARS-CoV-2-positive mothers to determine the rate of mother-to-baby transmission of SARS-CoV-2 and its effect on short-term neonatal outcomes in Indian population. Nineteen babies turned out to be RT-PCR-positive for SARS-CoV-2, carrying a perinatal transmission rate of 9.8%. Rates of prematurity and low birth weight were 12.8% and 18.9% in the neonatal group, respectively. On comparing SARS-CoV-2-positive (n = 19) and negative (n = 177) neonatal groups, rate of prematurity, hospital admission rate, and death rate were higher in the former group. The placental positivity rate for SARS-CoV-2 was 8.1%, but no relation was found between placental and neonatal infection.

摘要

母亲感染 SARS-CoV-2 可能对分娩和新生儿结局产生不利影响。作者前瞻性纳入了 193 名 SARS-CoV-2 阳性母亲所生的 196 名新生儿,以确定 SARS-CoV-2 在印度人群中从母亲到婴儿的传播率及其对短期新生儿结局的影响。19 名婴儿的 SARS-CoV-2 RT-PCR 检测结果呈阳性,围产期传播率为 9.8%。新生儿组的早产率和低出生体重率分别为 12.8%和 18.9%。在比较 SARS-CoV-2 阳性(n=19)和阴性(n=177)新生儿组时,前者的早产率、住院率和死亡率更高。SARS-CoV-2 在胎盘的阳性率为 8.1%,但胎盘和新生儿感染之间没有关系。

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