Department of Neonatology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
Division of Newborn Medicine, Department of Pediatrics, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.
J Perinatol. 2021 May;41(5):940-951. doi: 10.1038/s41372-020-00874-x. Epub 2020 Dec 8.
The coronavirus disease 2019 (COVID-19) pandemic, resulting from infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has caused severe and widespread illness in adults, including pregnant women, while rarely infecting neonates. An incomplete understanding of disease pathogenesis and viral spread has resulted in evolving guidelines to reduce transmission from infected mothers to neonates. Fortunately, the risk of neonatal infection via perinatal/postnatal transmission is low when recommended precautions are followed. However, the psychosocial implications of these practices and racial/ethnic disparities highlighted by this pandemic must also be addressed when caring for mothers and their newborns. This review provides a comprehensive overview of neonatal-perinatal perspectives of COVID-19, ranging from the basic science of infection and recommendations for care of pregnant women and neonates to important psychosocial, ethical, and racial/ethnic topics emerging as a result of both the pandemic and the response of the healthcare community to the care of infected individuals.
新型冠状病毒病 2019（COVID-19）大流行是由严重急性呼吸系统综合征冠状病毒 2（SARS-CoV-2）感染引起的，已导致包括孕妇在内的成年患者出现严重且广泛的疾病，而很少感染新生儿。由于对疾病发病机制和病毒传播的了解不完整，因此制定了指南以降低感染母亲向新生儿传播的风险。幸运的是，当遵循推荐的预防措施时，通过围产期/产后传播导致新生儿感染的风险较低。然而，在照顾母亲及其新生儿时，还必须解决这些做法的心理社会影响以及大流行所凸显的种族/民族差异。本综述全面概述了 COVID-19 的新生儿围产期观点，从感染的基础科学以及对孕妇和新生儿的护理建议，到由于大流行和医疗保健界对感染者护理的反应而出现的重要心理社会、伦理和种族/民族主题。
