Department of Cardiac Surgery, University of Ottawa Heart Institute, Ottawa, Canada; Department of Cardiovascular Surgery, University Heart Center Freiburg, Bad Krozingen, Germany.
Department of Cardiac Surgery, University of Ottawa Heart Institute, Ottawa, Canada.
Prog Cardiovasc Dis. 2022 May-Jun;72:15-20. doi: 10.1016/j.pcad.2022.06.008. Epub 2022 Jun 25.
Acquired valvular heart disease is associated with increased mortality and morbidity. While the etiology of the valvular dysfunction determines the mode of treatment, over 100,000 valve operations are performed annually in the US with the use of bioprosthetic valves comprising up to 90%. While bioprosthetic valves do not require life long anticoagulation, the incidence of prosthetic valve thrombosis is continuously increasing. This article reviews the current status on diagnosis, treatment modalities and management of bioprosthetic valve thrombosis.
获得性心脏瓣膜病与死亡率和发病率的增加有关。虽然瓣膜功能障碍的病因决定了治疗方式，但美国每年有超过 10 万例瓣膜手术，其中使用生物瓣的比例高达 90%。虽然生物瓣不需要终身抗凝，但人工心脏瓣膜血栓形成的发生率持续增加。本文回顾了生物瓣血栓形成的诊断、治疗方法和管理的现状。
