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缓和医疗对需要体外膜肺氧合的 COVID-19 患者的影响。

Palliative Care Impact on COVID-19 Patients Requiring Extracorporeal Membrane Oxygenation.

机构信息

Department of Medicine (A.G., E.N.O.), Section of Geriatrics and Palliative Medicine, Baylor College of Medicine, Houston, Texas, USA.

Department of Medicine (A.G., E.N.O.), Section of Geriatrics and Palliative Medicine, Baylor College of Medicine, Houston, Texas, USA.

出版信息

J Pain Symptom Manage. 2022 Oct;64(4):e181-e187. doi: 10.1016/j.jpainsymman.2022.06.013. Epub 2022 Jun 25.

Abstract

CONTEXT

Patients with severe respiratory failure from COVID-19 refractory to conventional therapies may be treated with extracorporeal membrane oxygenation (ECMO). ECMO requirement is associated with high mortality and prolonged hospital course. ECMO is a high-resource intervention with significant burdens placed on caregivers and families with limited data on the integration of palliative care consultation (PCC).

OBJECTIVES

To explore the role of standard vs. automatic PCC in the management of COVID patients on ECMO.

METHODS

Retrospective chart review of all COVID patients on ECMO admitted from March 2020 to May 2021 at a large volume academic medical center with subsequent analysis.

RESULTS

Forty-eight patients were included in the analysis. Twenty-six (54.2%) received PCC of which 42% of consults were automatically initiated. PCC at any point in admission was associated with longer duration on ECMO (24.5 vs. 37 days; P < 0.05). Automatic PCC resulted in more family meetings than standard PCC (0 vs. 3; P < 0.05) and appears to trend with reduced time on ECMO, shorter length of stay, and higher DNAR rates at death, though results were not significant. Decedents not receiving PCC had higher rates of no de-escalation of interventions at time of death (31% vs. 11%), indicating full intensive care measures continued through death.

CONCLUSIONS

Among patients with COVID-19 receiving ECMO, PCC may be associated with a shift to DNAR status particularly with automatic PCC. There may be a further impact on length of stay, duration of time on ECMO and care plan at end of life.

摘要

背景

患有 COVID-19 导致的严重呼吸衰竭且对常规治疗无反应的患者可能需要接受体外膜肺氧合(ECMO)治疗。ECMO 的需求与高死亡率和延长的住院时间相关。ECMO 是一种高资源干预措施,给护理人员和患者家庭带来了巨大负担,而关于姑息治疗咨询(PCC)整合的数据有限。

目的

探讨标准与自动 PCC 在 COVID-19 患者 ECMO 管理中的作用。

方法

对 2020 年 3 月至 2021 年 5 月在一家大型学术医疗中心接受 ECMO 治疗的所有 COVID 患者进行回顾性病历审查,随后进行分析。

结果

共纳入 48 例患者进行分析。26 例(54.2%)接受了 PCC,其中 42%的咨询是自动启动的。入院时任何时候进行 PCC 与 ECMO 时间延长相关(24.5 天 vs. 37 天;P < 0.05)。自动 PCC 比标准 PCC 举行更多的家庭会议(0 次 vs. 3 次;P < 0.05),且似乎与 ECMO 时间缩短、住院时间缩短和死亡时更高的 DNAR 率相关,尽管结果无统计学意义。未接受 PCC 的死者在死亡时无干预措施降级的比例更高(31% vs. 11%),表明在死亡过程中继续采用全面的重症监护措施。

结论

在接受 ECMO 治疗的 COVID-19 患者中,PCC 可能与向 DNAR 状态转变相关,尤其是在进行自动 PCC 时。在死亡时的干预措施降级、住院时间和生命末期的护理计划方面可能会产生进一步的影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1b37/9233556/55f786904021/gr1_lrg.jpg

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