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体外生命支持的姑息治疗:来自国家住院患者样本的见解。

Palliative Care for Extracorporeal Life Support: Insights From the National Inpatient Sample.

机构信息

Division of Cardiac Surgery, Cardiovascular Outcomes Research Laboratories (CORELAB), David Geffen School of Medicine, 155697University of California, Los Angeles, CA, USA.

出版信息

Am Surg. 2021 Dec;87(10):1621-1626. doi: 10.1177/00031348211024232. Epub 2021 Jun 14.

Abstract

BACKGROUND

Providing temporary cardiopulmonary support, extracorporeal membrane oxygenation (ECMO) carries a high risk of mortality. Palliative care (PC) may facilitate a patient-centered approach to end-of-life care in order to aid symptom management and provide psychosocial support to families. The present study aimed to identify factors associated with PC consultation and its impact on resource utilization in ECMO.

STUDY DESIGN

All adults placed on ECMO at a PC capable center were identified in the 2006-2017 National Inpatient Sample. Indications for ECMO were identified using diagnosis codes and classified into postcardiotomy syndrome, respiratory failure, cardiogenic shock, mixed cardiopulmonary failure, and transplant related.

RESULTS

Of 41 122 patients undergoing ECMO, 20 514 (49.9%) died in the same hospitalization. Of those, 3951 (19.3%) received a PC consult. Use of PC consults increased significantly from 5.5% in 2006 to 22.8% in 2017 (nptrend<.001). After multivariable risk adjustment, PC consults did not affect costs (β: -$7341, 95% CI: -22 572 to +7888) or duration of hospitalizations (β: -.37 days, 95% CI: -2.76 to +2.02).

CONCLUSION

Utilization of PC does not appear to negatively influence resource utilization among non-survivors of ECMO. Increased adaptation of PC in ECMO may improve end-of-life care, a factor that deserves future study.

摘要

背景

体外膜肺氧合(ECMO)提供临时心肺支持,其死亡率很高。姑息治疗(PC)可以促进以患者为中心的临终关怀方法,以帮助管理症状并为家庭提供社会心理支持。本研究旨在确定与 PC 咨询相关的因素及其对 ECMO 中资源利用的影响。

研究设计

在 2006-2017 年国家住院患者样本中,确定了在具备 PC 能力的中心接受 ECMO 的所有成年人。使用诊断代码确定 ECMO 的适应症,并将其分为心脏手术后综合征、呼吸衰竭、心源性休克、混合心肺衰竭和移植相关。

结果

在接受 ECMO 的 41122 名患者中,20514 名(49.9%)在同一次住院期间死亡。其中,3951 名(19.3%)接受了 PC 咨询。从 2006 年的 5.5%到 2017 年的 22.8%,PC 咨询的使用率显著增加(nptrend<.001)。经过多变量风险调整后,PC 咨询并未影响成本(β:-7341 美元,95%CI:-22572 至 +7888)或住院时间(β:-0.37 天,95%CI:-2.76 至 +2.02)。

结论

在 ECMO 非幸存者中,PC 的使用似乎不会对资源利用产生负面影响。在 ECMO 中增加 PC 的应用可能会改善临终关怀,这是一个值得未来研究的因素。

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