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[自身免疫性肝炎的诊断和管理指南(2021年)]

[Guidelines on the diagnosis and management of autoimmune hepatitis (2021)].

出版信息

Zhonghua Gan Zang Bing Za Zhi. 2022 May 20;30(5):482-492. doi: 10.3760/cma.j.cn112138-20211112-00796.

Abstract

Autoimmune hepatitis (AIH) is characterized by elevated serumaminotransferase and immunoglobulin G levels, seropositive results for autoantibodies and moderate to severe interface hepatitis in histologic findings. It will be most helpful in improving survival and life quality, if patients are diagnosed in the early stage and treated appropriately, which also helps relieve social medical burdens. Chinese consensus on the diagnosis and management of autoimmune hepatitis (2015) has contributed to standardizing the diagnosis and treatment of AIH.On the basis of the first consensus, at the end of 2021, under the organization of Chinese Society of Hepatology, experts devise this guide with latest advances aiming to further improve the level of diagnosis and management of autoimmune hepatitis.

摘要

自身免疫性肝炎(AIH)的特征是血清氨基转移酶和免疫球蛋白G水平升高、自身抗体血清学阳性以及组织学检查结果显示中度至重度界面性肝炎。如果患者能在早期得到诊断并接受适当治疗,将最有助于提高生存率和生活质量,这也有助于减轻社会医疗负担。《自身免疫性肝炎诊断和治疗中国专家共识(2015年版)》有助于规范AIH的诊断和治疗。在首个共识的基础上,2021年底,在中华医学会肝病学分会的组织下,专家们结合最新进展制定了本指南,旨在进一步提高自身免疫性肝炎的诊断和管理水平。

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