[血液吸附在慢性肝病患者治疗中的应用]

[Use of hemosorption in the treatment of patients with chronic liver diseases].

作者信息

Radchenko V G, Litvinov A S, Vinogradova G L

出版信息

Ter Arkh. 1987;59(2):118-21.

Abstract

The influence of hemosorption in multimodality therapy of 71 patients with chronic liver diseases was studied. Together with clinical improvement of the health status hemosorption was followed by a decrease in the concentration of bilirubin, cholesterol and gamma-globulins, ALT activity, the level of the thymol test, IgA, IgG and CIC. The content of T-lymphocytes and their subpopulation changed very little. Hemosorption efficacy was more marked in chronic active hepatitis and at initial stages of biliary cirrhosis than at the dystrophic stage of biliary cirrhosis. The use of hemosorption in multimodality therapy of patients with chronic liver diseases contributed to faster clinical improvement, return of biochemical and immunological indices to normal.

摘要

研究了血液吸附对71例慢性肝病患者多模式治疗的影响。随着健康状况的临床改善，血液吸附后胆红素、胆固醇和γ-球蛋白浓度、ALT活性、麝香草酚浊度试验水平、IgA、IgG和CIC均下降。T淋巴细胞及其亚群的含量变化很小。血液吸附在慢性活动性肝炎和胆汁性肝硬化早期的疗效比胆汁性肝硬化营养不良期更显著。在慢性肝病患者的多模式治疗中使用血液吸附有助于更快地实现临床改善，使生化和免疫指标恢复正常。