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[高压氧疗对十二指肠溃疡患者自由基过程及胃酸分泌的影响]

[Effect of hyperbaric oxygenation on free-radical processes and gastric acid production in patients with duodenal ulcer].

作者信息

Zvershkhanovskiĭ F A, Zhulkevich I V

出版信息

Ter Arkh. 1987;59(2):53-5.

PMID:3576476
Abstract

Ascorbate- and NADPH-dependent free radical oxidation, the state of the antioxidant system, hydrogen iron secretion rate (HISR) and acid production kinetic function (AFKF) were investigated in 38 patients with duodenal ulcer to study the effect of hyperbaric oxygenation on free radical processes and gastric acid production. Assessment of the results of the study indicated the activation of NADPH-dependent free radical lipid oxidation, HISR acceleration and AFKF enhancement during hyperbaric oxygenation in the treatment of duodenal ulcer which required adjuvant corrective therapy.

摘要

对38例十二指肠溃疡患者的抗坏血酸和NADPH依赖的自由基氧化、抗氧化系统状态、氢铁分泌率(HISR)和酸产生动力学功能(AFKF)进行了研究,以探讨高压氧疗对自由基过程和胃酸产生的影响。研究结果评估表明,在十二指肠溃疡治疗的高压氧疗过程中,NADPH依赖的自由基脂质氧化被激活,HISR加速,AFKF增强,这需要辅助纠正治疗。

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