Moon Hwi Hyun, Choi Eun Jung, Yun Sang Ho, Kim Youn Chul, Premkumar Thathan, Song Changsik
Department of Chemistry, Sungkyunkwan University Suwon Gyeonggi 16419 Republic of Korea
Department of Chemical Engineering, Sungkyunkwan University Suwon Gyeonggi 16419 Republic of Korea.
RSC Adv. 2022 Jun 15;12(28):17740-17746. doi: 10.1039/d2ra02711a. eCollection 2022 Jun 14.
The usage of aqueous lubricants in eco-friendly bio-medical friction systems has attracted significant attention. Several bottle-brush polymers with generally ionic functional groups have been developed based on the structure of biological lubricant lubricin. However, hydrophilic nonionic brush polymers have attracted less attention, especially in terms of wear properties. We developed bottle-brush polymers (BP) using hydrophilic 2-hydroxyethyl methacrylate (HEMA), a highly biocompatible yet nonionic molecule. The lubrication properties of polymer films were analyzed in an aqueous state using a ball-on-disk, which revealed that BPHEMA showed a lower aqueous friction coefficient than linear poly(HEMA), even lower than hyaluronic acid (HA) and polyvinyl alcohol (PVA), which are widely used as lubricating polymers. Significantly, we discovered that the combination of HA, PVA, and BPHEMA is demonstrated to be essential in influencing the surface wear properties; the ratio of 1 : 2 (HA : BPHEMA) had the maximum wear resistance, despite a slight increase in the aqueous friction coefficient.
水性润滑剂在环保型生物医学摩擦系统中的应用已引起广泛关注。基于生物润滑剂润滑素的结构，人们已开发出几种通常带有离子官能团的瓶刷聚合物。然而，亲水性非离子刷聚合物受到的关注较少，尤其是在磨损性能方面。我们使用甲基丙烯酸2-羟乙酯（HEMA）开发了瓶刷聚合物（BP），HEMA是一种具有高度生物相容性的非离子分子。使用球盘法在水相中分析了聚合物薄膜的润滑性能，结果表明BPHEMA在水相中的摩擦系数低于线性聚（HEMA），甚至低于广泛用作润滑聚合物的透明质酸（HA）和聚乙烯醇（PVA）。值得注意的是，我们发现HA、PVA和BPHEMA的组合对影响表面磨损性能至关重要；尽管水相摩擦系数略有增加，但1∶2（HA∶BPHEMA）的比例具有最大的耐磨性。
