Basaran Burhan, Faiz Ozlem
Department of Travel, Tourism and Recreation Services, Ardeşen Vocational School, Recep Tayyip Erdogan University, 53100, Rize, Turkey.
Department of Chemistry, Faculty of Arts and Sciences, Recep Tayyip Erdogan University, 53100, Rize, Turkey.
Iran J Pharm Res. 2022 Apr 3;21(1):e123948. doi: 10.5812/ijpr.123948. eCollection 2022 Dec.
In this study, exposure risk assessment was made by determining the acrylamide levels of some traditional foods frequently consumed by the Turkish society and registered geographical indication. For this purpose, acrylamide levels of 20 traditional foods [7 meat products, 3 loaves of bread, 3 bagels (simit), and 7 desserts] obtained from different bakeries, patisseries, and restaurants were determined by LC-MS/MS. Acrylamide levels were determined between 12.7 - 299 μg/kg in meat products, 11.8 - 69.3 μg/kg in bread, 11.8 - 179 μg/kg in bagels, 11.7 - 85.0 μg/kg in baked desserts, and 32.3 - 527 μg/kg in deep-fried desserts. According to the portion size, the food with the highest acrylamide level in meat products is Adana kebab (17.70 μg/180 g). Formulation and cooking techniques are thought to be the main determinants of acrylamide level detected in traditional foods. Dietary acrylamide exposure was calculated according to the deterministic model. Exposure was calculated as 0.20, 0.53, and 0.98 μg/kg bw per day for good, average and bad scenarios, respectively. The calculated acrylamide exposure value is below the reference values stated by FAO/WHO. The acrylamide dietary exposure was not of concern concerning neurotoxicity and carcinogenicity. The results can be used to reduce acrylamide levels in foods and risk assessment studies.
在本研究中,通过测定土耳其社会经常食用的一些传统食品和注册地理标志食品中的丙烯酰胺含量,进行了暴露风险评估。为此,采用液相色谱-串联质谱法(LC-MS/MS)测定了从不同面包店、糕点店和餐馆获取的20种传统食品[7种肉类产品、3种面包、3种百吉饼(苏梅特)和7种甜点]中的丙烯酰胺含量。肉类产品中的丙烯酰胺含量在12.7 - 299微克/千克之间,面包中为11.8 - 69.3微克/千克,百吉饼中为11.8 - 179微克/千克,烘焙甜点中为11.7 - 85.0微克/千克,油炸甜点中为32.3 - 527微克/千克。根据食用份量,肉类产品中丙烯酰胺含量最高的食品是阿达纳烤肉串(17.70微克/180克)。配方和烹饪技术被认为是传统食品中检测到的丙烯酰胺含量的主要决定因素。根据确定性模型计算膳食丙烯酰胺暴露量。在良好、中等和不良情况下,暴露量分别计算为每天0.20、0.53和0.98微克/千克体重。计算出的丙烯酰胺暴露值低于粮农组织/世卫组织规定的参考值。丙烯酰胺膳食暴露在神经毒性和致癌性方面无需担忧。这些结果可用于降低食品中的丙烯酰胺含量以及风险评估研究。