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评估土耳其人口的膳食丙烯酰胺暴露水平:对人类健康的新威胁。

Estimation of the Dietary Acrylamide Exposure of the Turkish Population: An Emerging Threat for Human Health.

机构信息

Department of Nutrition and Dietetics, Faculty of Health Sciences, Recep Tayyip Erdogan University, Rize 53100, Türkiye.

出版信息

Nutrients. 2024 Sep 13;16(18):3088. doi: 10.3390/nu16183088.

DOI:10.3390/nu16183088
PMID:39339688
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11434696/
Abstract

Acrylamide is a contaminant formed during heat treatment that poses potential health risks and occurs naturally in foods. Therefore, it is crucial to evaluate exposure from the consumption of foods containing acrylamide since dietary exposure continues throughout life. In this study, the acrylamide exposure level of people living in Türkiye is estimated. Consumption of a total of 28 foods in 9 different food groups was calculated using a deterministic model under two different scenarios. The exposure levels were evaluated in terms of carcinogenic, non-carcinogenic and neurotoxic health risks. The daily total acrylamide exposure levels of individuals aged 15 and older were determined as 58 µg/day (0.85 µg/kg bw/day) and 196 µg/day (2.80 µg/kg bw/day) for the good and bad scenarios, respectively. The highest daily acrylamide exposure in the good scenario came from brewed black tea (29%), whereas French fries (50%) were the source of highest daily acrylamide exposure in the bad scenario. According to the hazard index (HI) and margin of exposure (MOE) data, the good scenario (all food) is considered safe, while the bad scenario (all food) has potential and serious health risks. According to the carcinogenic risk (CR) data, both scenarios carry significant health risks. It is therefore important that consumers, producers and official institutions collaborate and take measures to reduce acrylamide exposure.

摘要

丙烯酰胺是一种在热处理过程中形成的污染物,具有潜在的健康风险,并且天然存在于食品中。因此,评估人们从食用含丙烯酰胺食品中所摄入的丙烯酰胺量非常重要,因为这种摄入会持续一生。在这项研究中,估算了生活在土耳其的人群的丙烯酰胺暴露水平。使用确定性模型,在两种不同的情景下,计算了来自 9 个不同食品组的 28 种食品的总消耗量。通过致癌、非致癌和神经毒性健康风险来评估暴露水平。15 岁及以上个体的每日总丙烯酰胺暴露水平分别为 58 µg/天(0.85 µg/kg bw/天)和 196 µg/天(2.80 µg/kg bw/天),这两种情景分别为好情景和差情景。好情景下,每日丙烯酰胺暴露量最高的食物是冲泡黑茶(29%),而在差情景下,每日丙烯酰胺暴露量最高的食物是炸薯条(50%)。根据危害指数(HI)和暴露量边际(MOE)数据,好情景(所有食物)被认为是安全的,而差情景(所有食物)存在潜在的严重健康风险。根据致癌风险(CR)数据,两种情景都存在重大的健康风险。因此,消费者、生产者和官方机构需要合作并采取措施来降低丙烯酰胺的暴露量。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8122/11434696/d8471e084475/nutrients-16-03088-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8122/11434696/12a9a0fb6f8a/nutrients-16-03088-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8122/11434696/1445980e4cf8/nutrients-16-03088-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8122/11434696/530db82669ec/nutrients-16-03088-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8122/11434696/c733ccf3bf09/nutrients-16-03088-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8122/11434696/d8471e084475/nutrients-16-03088-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8122/11434696/12a9a0fb6f8a/nutrients-16-03088-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8122/11434696/1445980e4cf8/nutrients-16-03088-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8122/11434696/530db82669ec/nutrients-16-03088-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8122/11434696/c733ccf3bf09/nutrients-16-03088-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8122/11434696/d8471e084475/nutrients-16-03088-g005.jpg

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