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Behçet 病患者肺血栓栓塞的组织病理学。

Histopathology of pulmonary thromboembolism in a patient with Behçet's disease.

机构信息

Department of Internal Medicine, Teikyo University School of Medicine, Tokyo, Japan.

Department of Pathology, Teikyo University School of Medicine, Tokyo, Japan.

出版信息

Clin Exp Rheumatol. 2022 Sep;40(8):1584-1587. doi: 10.55563/clinexprheumatol/il4pc7. Epub 2022 Jun 15.

Abstract

Pulmonary involvement in vascular Behçet's disease (BD) (VBD) is a serious manifestation. Among the pulmonary manifestations, pulmonary embolism is considered a rare manifestation because deep vein thrombosis (DVT) has been thought to detach from the vessel wall, whereas pulmonary thrombus has been suggested to result from in situ pulmonary arteritis.In this case report, we present histopathological evidence of pulmonary embolism derived from DVT in an autopsy case of VBD. This observation emphasises that DVT causes pulmonary embolism in BD, indicating that anticoagulants are required for its prevention.

摘要

血管性贝赫切特病(VBD)的肺部受累是一种严重的表现。在肺部表现中,肺栓塞被认为是一种罕见的表现,因为深静脉血栓(DVT)被认为是从血管壁上脱落的,而肺血栓则被认为是由原位肺血管炎引起的。在本病例报告中,我们展示了 VBD 尸检病例中源自 DVT 的肺栓塞的组织病理学证据。这一观察结果强调了 DVT 可导致 BD 中的肺栓塞,表明需要抗凝剂来预防。

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