School of Horticulture and Plant Protection, Yangzhou University, Yangzhou, China.
Pest Manag Sci. 2022 Oct;78(10):4407-4416. doi: 10.1002/ps.7061. Epub 2022 Jul 19.
Developing pesticide-controlled release formulations with foliage adhesion has become the focus of current research in the field of crop protection. In this study, an excellent adhesive nanocapsule loaded with emamectin benzoate (Eb@PDA) was prepared via emulsion interfacial polymerization based on the self-polymerization ability and adhesion properties of polydopamine (PDA).
The physicochemical properties of the Eb@PDA were characterized by scanning electron microscopy, transmission electron microscopy, particle size statistics, Fourier transform infrared spectroscopy and X-ray diffraction. The Eb@PDA presented a regular spherical shape, with an average particle size of 163.8 nm. Compared with conventional formulations, it had higher pesticide-loading content (34%) and excellent adhesion onto corn leaf. In addition, Eb@PDA showed sustained-release characteristics, facilitating the release of Eb at low pH and high temperature. Eb@PDA could effectively protect Eb against photodegradation and had a longer effective period for controlling Spodoptera frugiperda and Spodoptera exigua. Furthermore, acute toxicity tests showed that the 50% lethal concentration (LC ) was 80.91 and 57.91 mg kg at 7 and 14 days, respectively, indicating a lower toxicity of the Eb@PDA to earthworms. The cells (L02) treated with Eb@PDA showed a higher cell viability but a lower apoptosis rate (only 5.75%), demonstrating the lower cytotoxicity of the Eb@PDA.
The self-prepared Eb@PDA could be used as a formulation with the advantages of slow release, UV shielding, strong leaf adhesion, superior insecticidal properties, sustained effectiveness and biosafety. It will also facilitate the development of an efficient and safe pesticide delivery system. © 2022 Society of Chemical Industry.
开发具有叶附著力的农药控释制剂已成为当前作物保护领域的研究重点。在这项研究中，通过乳液界面聚合，利用聚多巴胺（PDA）的自聚合能力和粘附特性，制备了负载甲氨基阿维菌素苯甲酸盐（Eb@PDA）的优良粘附纳米胶囊。
通过扫描电子显微镜、透射电子显微镜、粒径统计、傅里叶变换红外光谱和 X 射线衍射对 Eb@PDA 的理化性质进行了表征。Eb@PDA 呈规则球形，平均粒径为 163.8nm。与传统制剂相比，它具有更高的农药载药量（34%），对玉米叶片具有优异的粘附性。此外，Eb@PDA 具有缓释特性，有利于 Eb 在低 pH 值和高温下释放。Eb@PDA 能有效保护 Eb 免受光降解，对控制玉米螟和斜纹夜蛾的有效期更长。此外，急性毒性试验表明，7 天和 14 天时的 50%致死浓度（LC ）分别为 80.91 和 57.91mg/kg，表明 Eb@PDA 对蚯蚓的毒性较低。用 Eb@PDA 处理的细胞（L02）表现出更高的细胞活力和更低的凋亡率（仅为 5.75%），表明 Eb@PDA 的细胞毒性较低。
自行制备的 Eb@PDA 可用作一种制剂，具有缓慢释放、屏蔽紫外线、强叶附著、优异的杀虫性能、持续效果和生物安全性等优点。它还将促进高效、安全的农药输送系统的发展。 © 2022 化学工业协会。
