Riesen W F, Muacevic B, Jaggi M
J Clin Chem Clin Biochem. 1978 Jul;16(7):387-9. doi: 10.1515/cclm.1978.16.7.387.
The EMIT homogeneous enzyme immunoassay for the determination of thyroxine (T4) was adapted to an automatic analyser (Type Kem-O-Mat) and compared with a conventional radioimmunoassay. Sera from 92 patients whose thyrometabolic status was being examined, and control sera with 3 different T4 concentrations were analysed by both methods. Day-to-day analyses of the control sera gave variation coefficients between 6 and 10% for both methods. The mean value for T4 in the patients sera was 111 nmol/l (8.6 microgram/dl) determined by the enzyme immunoassay and 109 nmol/l (8.5 microgram/dl) determined by the radioimmunoassay; the correlation coefficient was r = 0.9.
用于测定甲状腺素（T4）的EMIT均相酶免疫测定法被适配于自动分析仪（Kem - O - Mat型），并与传统放射免疫测定法进行比较。采用这两种方法分析了92例正在接受甲状腺代谢状态检查的患者的血清，以及含有3种不同T4浓度的对照血清。对照血清的日常分析结果表明，两种方法的变异系数均在6%至10%之间。通过酶免疫测定法测定的患者血清中T4的平均值为111 nmol/l（8.6微克/分升），通过放射免疫测定法测定的为109 nmol/l（8.5微克/分升）；相关系数为r = 0.9。
