Zhonghua Jie He He Hu Xi Za Zhi. 2022 Jul 12;45(7):651-666. doi: 10.3760/cma.j.cn112147-20220215-00120.
Patients with tuberculosis(TB) usually have abnormal immune function, and the host immunological status is closely related to the occurrence, development and outcome of TB. At present, the knowledge of immunotherapy of TB is obviously insufficient. In order to promote the application of new methods of TB immunotherapy in China and achieve the maximum possible gain of TB patients, the Chinese Society of Tuberculosis/Chinese Medical Association issued . This consensus described the immunological pathogenesis of TB, appropriate patients and goals of immunotherapy. Recommendations (reference evidence) on the application of immunotherapeutic preparations were put forward, with a description of the method of application, adverse reactions and precautions, so as to provide reference for clinical doctors for TB immunotherapy.
结核病(TB)患者通常免疫功能异常,宿主免疫状态与结核病的发生、发展及转归密切相关。目前,结核病免疫治疗的知识明显不足。为促进结核病免疫治疗新方法在中国的应用并使结核病患者获得最大可能的获益,中华医学会结核病学分会发布了本共识。该共识阐述了结核病的免疫发病机制、免疫治疗的适用患者及目标。提出了免疫治疗制剂应用的推荐意见(参考依据),并描述了应用方法、不良反应及注意事项,以便为临床医生进行结核病免疫治疗提供参考。