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基于2019年国内已故捐赠者数据对捐赠失败原因及改进措施的分析

Causes of donation failure and improvement measures analyzed based on data from domestic deceased donors in 2019.

作者信息

Cho Won-Hyun

机构信息

Korea Organ Donation Agency, Seoul, Korea.

出版信息

Korean J Transplant. 2020 Dec 31;34(4):219-230. doi: 10.4285/kjt.20.0040.

DOI:10.4285/kjt.20.0040
PMID:35770101
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9186859/
Abstract

In 2019, 1,630 organs were recovered from 450 brain death donors nationwide and were transplanted into 1,612 transplant recipients. However, considering that the number of potential brain-dead linked to the Korea Organ Donation Agency (KODA) information center was 2,484, only 18.1% of the linked brain-dead donated successfully. Of the 1,606 people who were available for family interviews, 67.0% refused to donate, so their cause analysis and countermeasures are needed. In particular, 203 reported cases died during the early period of donor evaluation, so we need a special concern on these cases. After consent, 67 cases failed to donate due to death or poor organ condition, and this raises the question of the possibility of shortening brain death management time. The average time interval from the first investigation to the completion of the second investigation (11.5 hours), until obtaining a flat electroencephalogram (5.3 hours) and conclusion of the brain death committee is 5.9 hours. Reducing unnecessary brain death management time is expected to improve the quality of organs and increase the number of organs to be recovered. Therefore, efforts to accurately identify and report potential brain death, and efforts to reduce the time spent in confirming brain death together with improving awareness of organ donation in people across the country are necessary to increase the number of deceased donors even in the current brain death management system. Implementation of donation after circulatory death for mortality case during the donor management is also urgent.

摘要

2019年,全国450名脑死亡供者共捐献了1630个器官,这些器官被移植给了1612名受者。然而,考虑到与韩国器官捐赠机构(KODA)信息中心关联的潜在脑死亡者数量为2484人,仅有18.1%的关联脑死亡者成功捐献。在1606名可进行家属访谈的人中,67.0%拒绝捐献,因此需要对其原因进行分析并采取应对措施。特别是,有203例报告病例在供者评估早期死亡,所以我们需要特别关注这些病例。在获得同意后,有67例因死亡或器官状况不佳而未能捐献,这就引发了缩短脑死亡管理时间可能性的问题。从首次检查到完成第二次检查的平均时间间隔为11.5小时,直到获得脑电图平线(5.3小时)以及脑死亡判定委员会得出结论的时间为5.9小时。减少不必要的脑死亡管理时间有望提高器官质量并增加可获取的器官数量。因此,即使在当前的脑死亡管理系统下,为了增加已故供者的数量,准确识别和报告潜在脑死亡的努力,以及与提高全国民众器官捐赠意识一起减少确认脑死亡所花费时间的努力都是必要的。在供者管理期间对死亡病例实施心脏死亡后捐献也很紧迫。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3aa6/9186859/e8eaf998626f/KJT-34-4-219-f10.jpg
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