Department of Gastroenterology, Daqing Oilfields General Hospital, Daqing, 163000 Heilongjiang, China.
Department of Neurology, Daqing Oilfields General Hospital, Daqing, 163000 Heilongjiang, China.
Comput Math Methods Med. 2022 Jun 20;2022:7086472. doi: 10.1155/2022/7086472. eCollection 2022.
The aim of this study was to explore the value of computed tomography (CT) images based on electronic health (E-health) combined with painless gastrointestinal endoscopy (PGE) in the diagnosis of neurocognitive function in patients with combined anesthesia of propofol and butorphanol tartrate. 126 patients undergoing PGE were selected as the research objects, and all were performed with CT perfusion imaging before and after anesthesia to obtain the cerebral blood volume (CBV), cerebral blood flow (CBF), mean transit time (MTT), and time to peak (TTP). The Montreal Cognitive Assessment (MoCA) was adopted to evaluate the cognitive function of patients. The results showed that after anesthesia, the levels of CBF and CBV in the left and right thalami, frontal lobe, and temporal lobe of the patients were lower than those before anesthesia, while TTP and MTT were higher than those before anesthesia ( < 0.05). The MoCA score after anesthesia was lower than that before anesthesia ( < 0.05). After anesthesia, the CBF, CBV, TTP, and MTT values of the left and right frontal lobes and left and right temporal lobes were significantly positively correlated with MoCA ( < 0.05). In conclusion, the brain CT image parameters based on E-health can clearly display the blood perfusion in the lesion area of the patient, which was beneficial to the PGE-assisted judgment of cognitive dysfunction in patients with propofol tartrate and butorphanol tartrate anesthesia. Therefore, CT-assisted PGE examination based on E-health had a certain clinical value in evaluating the neurocognitive function of patients.
本研究旨在探讨基于电子健康(E-health)的计算机断层扫描(CT)图像与无痛胃肠镜(PGE)结合在丙泊酚和酒石酸布托啡诺复合麻醉患者神经认知功能诊断中的价值。选择 126 例接受 PGE 的患者作为研究对象,所有患者均在麻醉前后进行 CT 灌注成像,以获得脑血容量(CBV)、脑血流量(CBF)、平均通过时间(MTT)和达峰时间(TTP)。采用蒙特利尔认知评估(MoCA)评估患者的认知功能。结果表明,麻醉后患者左右丘脑、额叶和颞叶的 CBF 和 CBV 水平低于麻醉前,而 TTP 和 MTT 高于麻醉前(<0.05)。麻醉后的 MoCA 评分低于麻醉前(<0.05)。麻醉后,左、右额叶和左、右颞叶的 CBF、CBV、TTP 和 MTT 值与 MoCA 呈显著正相关(<0.05)。综上所述,基于 E-health 的脑 CT 图像参数可以清楚地显示患者病变区域的血流灌注情况,有利于 PGE 辅助判断丙泊酚和酒石酸布托啡诺麻醉患者的认知功能障碍。因此,基于 E-health 的 CT 辅助 PGE 检查在评估患者神经认知功能方面具有一定的临床价值。