Department of Cardiology, Creighton University School of Medicine, Omaha, Nebraska, NE 68124, USA.
Department of Internal Medicine, Creighton University School of Medicine, Omaha, Nebraska, NE 68124, USA.
Future Cardiol. 2022 Sep;18(9):709-717. doi: 10.2217/fca-2021-0143. Epub 2022 Jun 30.
Cardiac troponin (cTn) can also be elevated in patients with non-cardiac illnesses. The utility of elevated cTn in patients with acute gastrointestinal bleeding (AGIB) is unclear. We retrospectively identified all patients admitted with AGIB who had cTn ordered. We assessed the prevalence, predictors and mortality. A total of 172 patients with AGIB were included in the study, of whom 17% had abnormal cTn. Predictors of elevated cTn were advanced age, lower BMI, coronary artery disease and chronic kidney disease. The abnormal cTn group had more cardiac consultation and procedures and longer length of stay. However, there was no difference in mortality between the two groups. Elevated cTn in patients with AGIB was associated with more cardiology consultation and downstream cardiac testing, greater delay to endoscopic evaluation and longer length of stay, without significantly affecting the mortality.
心肌肌钙蛋白 (cTn) 在非心脏疾病患者中也可能升高。cTn 在急性胃肠道出血 (AGIB) 患者中的作用尚不清楚。我们回顾性地确定了所有因 AGIB 入院且 cTn 检测结果异常的患者。我们评估了 cTn 异常的患病率、预测因素和死亡率。共有 172 例 AGIB 患者纳入研究，其中 17% 的患者 cTn 检测结果异常。cTn 升高的预测因素为年龄较大、BMI 较低、冠心病和慢性肾脏病。cTn 异常组的心脏咨询和检查更多，住院时间更长。然而，两组之间的死亡率没有差异。AGIB 患者的 cTn 升高与更多的心脏病学咨询和下游心脏检查、内镜评估的延迟时间更长和住院时间延长有关，但对死亡率没有显著影响。
