Feldman R G
Yale J Biol Med. 1987 Mar-Apr;60(2):179-86.
The nervous system is vulnerable to the effects of certain chemicals and physical conditions found in the work environment. The activities of an occupational neurologist focus on the evaluation of patients with neurological disorders caused by occupational or environmental conditions. When one is making a differential diagnosis in patients with neurological disorders, the possibility of toxic exposure or encounters with physical factors in the workplace must not be overlooked. Central to an accurate clinical diagnosis is the patient's history. A diagnosis of an occupational or environmental neurological problem requires a careful assessment of the clinical abnormalities and confirmation of these disabilities by objective tests such as nerve conduction velocity, evoked potentials, electroencephalogram, neuropsychological batteries, or nerve biopsy. On the basis of information about hazards in the workplace, safety standards and environmental and biological monitoring can be implemented in the workplace to reduce the risks of undue injury. Clinical manifestations of headache, memory disturbance, and peripheral neuropathy are commonly encountered presentations of the effects of occupational hazards. Physicians in everyday clinical practice must be aware of the signs and symptoms associated with exposure to possible neurotoxins and work methods. Occupational and environmental circumstances must be explored when evaluating patients with neurologic disorders.
神经系统易受工作环境中某些化学物质和物理条件的影响。职业神经科医生的工作重点是评估由职业或环境因素引起的神经系统疾病患者。在对神经系统疾病患者进行鉴别诊断时,绝不能忽视工作场所中毒物暴露或接触物理因素的可能性。准确的临床诊断关键在于患者的病史。诊断职业性或环境性神经问题需要仔细评估临床异常情况,并通过神经传导速度、诱发电位、脑电图、神经心理测试组或神经活检等客观测试来证实这些功能障碍。根据工作场所危害信息,可在工作场所实施安全标准以及环境和生物监测,以降低过度损伤的风险。头痛、记忆障碍和周围神经病变是职业危害影响常见的临床表现。日常临床实践中的医生必须了解与接触可能的神经毒素及工作方式相关的体征和症状。在评估神经系统疾病患者时,必须探究职业和环境情况。