Sińczuk-Walczak Halina, Szymczak Maria, Aniołczyk Halina, Brzeźnicki Slawomir, Raźniewska Grazyna, Trzcinka-Ochocka Małgorzata, Matczak Wanda
Przychodni Chorób Zawodowych Instytutu Medycyny Pracy, Lodzi.
Med Pr. 2006;57(1):7-13.
The authors present the results of medical examinations of workers employed in an aluminum electrolysis plant with occupational exposure to aluminum dust, polycyclic aromatic hydrocarbons, and magnetic field.
The study covered a selected group of 39 male workers (mean age, 44,9; SD = 7.5 years; range 29-55 years) involved in the aluminum production. Their employment duration ranged between 5 and 32 years (mean, 17.8; SD = 6.7 years). Urine aluminum concentrations in workers ranged from 8.9 to 70.2 microg/g creatinine (mean, 31.72; SD = 18.3 microg/g creatinine). Urine 1-hydroxypyrene concentrations recorded in workers ranged from 0.67 to 10.09 microg/g creatinine (mean, 3.42; SD = 2.1 microg/g creatinine). The control group consisted of 39 men matched by gender, age and work shifts.
Clinical symptoms, such as headache (46.2%), increased emotional irritability (66.7%), concentration difficulty (25.6%), insomnia (30.8%), hypersomnia (15.4%), and mood lability (10.3%) predominated among functional disorders of the nervous system in workers chronically exposed to chemical and physical factors. The objective neurological examinations did not reveal organic lesions in the central or peripheral nervous system. In EEG recordings, classified as abnormal, paroxysmal changes were most common (20.5%).
The authors emphasized great difficulty in evaluating the combined effects of toxic and physical factors exerted on the nervous system.
作者展示了对一家铝电解厂中职业性接触铝尘、多环芳烃和磁场的工人进行医学检查的结果。
该研究涵盖了一组选定的39名男性工人（平均年龄44.9岁；标准差 = 7.5岁；年龄范围29 - 55岁），他们参与铝生产工作。其工作年限在5至32年之间（平均17.8年；标准差 = 6.7年）。工人们尿铝浓度范围为8.9至70.2微克/克肌酐（平均31.72微克/克肌酐；标准差 = 18.3微克/克肌酐）。工人们尿中1 - 羟基芘浓度范围为0.67至10.09微克/克肌酐（平均3.42微克/克肌酐；标准差 = 2.1微克/克肌酐）。对照组由39名在性别、年龄和工作班次上匹配的男性组成。
在长期接触化学和物理因素的工人中，神经系统功能障碍主要表现为临床症状，如头痛（46.2%）、情绪易激惹增加（66.7%）、注意力难以集中（25.6%）、失眠（30.8%）、嗜睡（15.4%）和情绪不稳定（10.3%）。客观的神经学检查未发现中枢或周围神经系统的器质性病变。在脑电图记录中，被归类为异常的，阵发性变化最为常见（20.5%）。
作者强调评估有毒和物理因素对神经系统的综合影响存在很大困难。
