Reynolds E H
Yale J Biol Med. 1987 Mar-Apr;60(2):79-83.
Recent community- and hospital-based studies of epilepsy from its onset suggest a much better prognosis than previously recognized, with about three-quarters of patients entering long-term remission on current medication. The first two years of medication are crucial in determining longer-term prognosis. Early effective therapy may be important in preventing the evolution of chronic epilepsy. Adverse prognostic factors include brain lesions, neuropsychiatric handicaps, and poor compliance.
近期基于社区和医院的癫痫发病研究表明,其预后比之前认为的要好得多,约四分之三的患者通过目前的药物治疗进入长期缓解期。药物治疗的头两年对确定长期预后至关重要。早期有效治疗对于预防慢性癫痫的发展可能很重要。不良预后因素包括脑损伤、神经精神障碍和依从性差。