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肉毒毒素在老年护理居民中风后痉挛性手部溃疡管理中的作用。

Role of botulinum toxin in the management of hand ulceration due to post-stroke spasticity among aged care residents.

机构信息

MBBS, MD, FAFRM, Associate Professor, Department of Rehabilitation Medicine, University of Adelaide, SA; Central Adelaide Local Health Network (CALHN), SA; The Queen Elizabeth Hospital, SA.

MBBS, FAFRM, Rehabilitation Registrar, Department of Rehabilitation Medicine, University of Adelaide, SA; Central Adelaide Local Health Network (CALHN), SA; The Queen Elizabeth Hospital, SA.

出版信息

Aust J Gen Pract. 2022 Jul;51(7):484-489. doi: 10.31128/AJGP-12-21-6279.

Abstract

BACKGROUND

Individuals with significant post-stroke impairments often move to residential care. The prevalence of spasticity is high among these residents. Palmar ulceration is an under-recognised complication of unmitigated post-stroke hand spasticity. The ulcerations are painful, emit offensive smell and cause significant suffering for the individuals and the carers.

OBJECTIVE

The aim of this article is to discuss the healing of these ulcerations by reducing spasticity in the hand muscles with botulinum toxin A (BoNTA) injection followed by dressing, splinting and hand therapy.

DISCUSSION

This article discusses the epidemiology, anatomy and clinical presentations of spastic hand ulcerations and mechanisms of action of BoNTA in alleviating the ulcers and related symptoms such as pain, sweating, offensive smell, and lessening the carer burden. The primary neuromuscular blocking action of BoNTA results in the opening of the hand, allowing dressing and ease of care. The toxin provides pain relief, inhibits excessive sweat production and causes vasodilatation, ultimately resulting in healing of the ulcerations.

摘要

背景

患有严重中风后遗症的患者通常会搬到养老院生活。这些居民中痉挛的发病率很高。手掌溃疡是未缓解的中风后手痉挛的一种被低估的并发症。溃疡疼痛、散发恶臭,给患者和护理人员带来极大的痛苦。

目的

本文旨在通过手部肌肉注射肉毒毒素 A(BoNTA)以减轻痉挛,再配合伤口处理、夹板固定和手部治疗,来讨论这些溃疡的愈合情况。

讨论

本文讨论了痉挛性手溃疡的流行病学、解剖学和临床表现,以及 BoNTA 缓解溃疡以及相关症状(如疼痛、出汗、恶臭和减轻护理人员负担)的作用机制。BoNTA 的主要神经肌肉阻断作用导致手部张开,便于伤口处理和护理。毒素可以缓解疼痛,抑制过度出汗,并导致血管扩张,最终使溃疡愈合。

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