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癌症姑息治疗患者使用泰国药用大麻后的症状管理和生活质量。

Symptom Management and Quality of Life of Palliative Cancer Patients After Being Administered with Thai Medicinal Cannabis.

机构信息

Faculty of Medicine, Mahasarakham University.

Public Health and Environmental Policy in Southeast Asia Research Cluster (PHEP-SEA), Mahasarakham University.

出版信息

Stud Health Technol Inform. 2022 Jun 29;295:450-453. doi: 10.3233/SHTI220762.

Abstract

This cross-sectional aimed to; 1) to explore the symptom management and quality of life (QoL) of palliative cancer patients, 2) to compare the perceived QoL outcomes between the patient who received standard treatment (ST) and who were treated with Cannabis treatment (CT). The study was carried out between 1st Febuary to 30st September 2021 from two hospitals in Roi-Et Regional Hospital and Sawang Dandin Crown Prince Hospital in Thailand. Using the EORTCQLQ-C30 and PPS assessment form, analysing with descriptive statistics, comparing mean scores for two patient groups by Independent T-test. The results found that patients of CT groups had a very high level of QoL while ST group had a high level. The consistency was statistically significant for overall QoL scores of CT higher than ST group (P-value < 001.0) both Cognitive functioning and Dyspnea symptoms (p-value=.05). However, the insomnia symptom indicated ST scores was higher than CT (P-value < 001.0). The results confirm that established the efficacy and safety of medical use of cannabis was benefit for patients. Therefore, it will be enhancing healthcare professionals to take opportunities for treatment for palliative patients' care.

摘要

本横断面研究旨在

1)探讨癌症姑息治疗患者的症状管理和生活质量(QoL),2)比较接受标准治疗(ST)和大麻治疗(CT)的患者的感知 QoL 结果。该研究于 2021 年 2 月 1 日至 9 月 30 日在泰国的罗伊-埃特地区医院和 Sawang Dandin 王储医院的两家医院进行。使用 EORTCQLQ-C30 和 PPS 评估表,进行描述性统计分析,通过独立 T 检验比较两组患者的平均评分。结果发现,CT 组患者的 QoL 水平非常高,而 ST 组患者的 QoL 水平较高。CT 组的整体 QoL 评分高于 ST 组(P 值<0.01),认知功能和呼吸困难症状的一致性具有统计学意义(P 值=0.05)。然而,失眠症状表明 ST 组的评分高于 CT 组(P 值<0.01)。研究结果证实了医用大麻的疗效和安全性,对患者有益。因此,它将增强医疗保健专业人员为姑息治疗患者提供治疗的机会。

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