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[神经垂体激素对大鼠不同类型行为反应的影响]

[Effect of hormones of the neurohypophysis on different types of behavioral responses in the rat].

作者信息

Shamakina I Iu, Titov S A, Nikonova A B, Voskresenskaia O G

出版信息

Zh Vyssh Nerv Deiat Im I P Pavlova. 1987 Jan-Feb;37(1):100-5.

PMID:3577400
Abstract

In experiments on male rats arginyl-vasopressin (AVP), lysyl-vasopressin (LVP) and vasotocin (VT) in doses of 0.005-0.010 mg/kg decreased motor activity and emotional behaviour in the open field test. In a dose of 0.001 mg/kg AVP significantly accelerated the elaboration of active avoidance; oxytocin delayed it, but LVP and VT had no significant influence. AVP also somewhat attenuated the elaboration of passive avoidance. None of the four studied peptides significantly affected the rate of elaboration of conditioned food-rewarded reaction to place.

摘要

在对雄性大鼠的实验中,剂量为0.005 - 0.010毫克/千克的精氨加压素(AVP)、赖氨加压素(LVP)和催产素(VT)在旷场试验中降低了运动活性和情绪行为。剂量为0.001毫克/千克的AVP显著加速了主动回避反应的形成;催产素使其延迟,但LVP和VT没有显著影响。AVP也在一定程度上减弱了被动回避反应的形成。所研究的四种肽均未对位置条件性食物奖励反应的形成速率产生显著影响。

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