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[使用赖氨加压素C末端片段消除条件性主动回避反应习得障碍]

[The elimination of disorders in the acquisition of a conditioned active avoidance reaction by using the C-termination fragment of lysyl vasopressin].

作者信息

Titov S A, Shamakina I Iu, Nikonova A B, Voskresenskaia O G, Kalikhevich V N

出版信息

Nauchnye Doki Vyss Shkoly Biol Nauki. 1988(6):45-8.

PMID:2844310
Abstract

In experiments with male white rats it was shown that 0.001 and 0.01 mg/kg of lysyl vasopressin C-terminal fragment--Pro-Lys-Gly (PLG) being injected intraperitoneally fails to influence the acquisition of active and passive avoidance and also T-maze food rewarded behaviour. The injection of PLG removed by disturbances of active avoidance caused by cyproheptadine and oxytocin. The inhibition of passive avoidance and food-rewarded behaviour was not removed by PLG.

摘要

在对雄性白鼠进行的实验中发现,腹腔注射0.001毫克/千克和0.01毫克/千克的赖氨加压素C末端片段——脯氨酸-赖氨酸-甘氨酸(PLG),不会影响主动和被动回避反应的习得,也不会影响T型迷宫食物奖励行为。PLG注射消除了由赛庚啶和催产素引起的主动回避反应干扰。但PLG并未消除被动回避反应和食物奖励行为的抑制。

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