Gasanov G G, Telegdi G, Ibragimov R Sh, Kadar T
Zh Vyssh Nerv Deiat Im I P Pavlova. 1986 Sep-Oct;36(5):905-12.
The influence of intraperitoneal injection of vasopressin (LVP), oxytocin (OXY) and their fragments (DGAVP, PLG) on the acquisition and extinction of conditioned food reflex was studied in rats. It was found that vasopressin and its fragments had a more pronounced specific effect on the higher nervous activity of the animals. This effect consisted in impairment of the performance of the conditioned food reflex while oxytocin had a tendency to improve its performance. On the ground of the obtained data it is suggested that administration of vasopressin may facilitate the memory function only under specific environmental conditions.
研究了腹腔注射血管加压素(LVP)、催产素(OXY)及其片段(DGAVP、PLG)对大鼠条件性食物反射的获得和消退的影响。发现血管加压素及其片段对动物的高级神经活动有更明显的特异性作用。这种作用表现为条件性食物反射的执行受损,而催产素有改善其执行的趋势。根据所得数据表明,血管加压素的给药可能仅在特定环境条件下促进记忆功能。