一名原发性中枢神经系统弥漫性大B细胞淋巴瘤年轻成年患者的系统性复发
Systemic Relapse in a Young Adult Patient with Primary CNS Diffuse Large B-Cell Lymphoma.
作者信息
Khorasanchi Adam, Benson Zachary, Hall Misty, Ebadirad Nelya, Gharavi Mohammad H, Willard Patrick, Chimzar Miranda, McKay John, Simmons Gary, Yazbeck Victor
机构信息
Department of Internal Medicine, Virginia Commonwealth University, Richmond, VA, USA.
Department of Pathology, Virginia Commonwealth University, Richmond, VA, USA.
出版信息
Case Rep Hematol. 2022 Jun 21;2022:7139661. doi: 10.1155/2022/7139661. eCollection 2022.
Primary central nervous system diffuse large B-cell lymphoma (PCNS-DLBCL) is a rare form of non-Hodgkin's lymphoma, characterized by an aggressive disease course. While CNS relapse is common, systemic relapse is rare with no consensus on optimal treatment. This paper presents an unusual case of advanced PCNS-DLBCL with systemic relapse, including adrenal gland involvement. A review of the existing literature and a discussion on the management of systemic relapse in PCNS-DLBCL is also provided.
原发性中枢神经系统弥漫性大B细胞淋巴瘤（PCNS-DLBCL）是一种罕见的非霍奇金淋巴瘤，其特点是疾病进程侵袭性强。虽然中枢神经系统复发很常见，但全身复发很少见，对于最佳治疗方案尚无共识。本文介绍了一例伴有全身复发（包括肾上腺受累）的晚期PCNS-DLBCL罕见病例。同时还对现有文献进行了综述，并讨论了PCNS-DLBCL全身复发的管理。
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