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糖尿病中的慢性炎症性脱髓鞘性多发性神经病(CIDP):诊断难题

Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) in Diabetes Mellitus: A Diagnostic Dilemma.

作者信息

Valentin Marcos, Coultas Ryan, Sottile Elisa

机构信息

Internal Medicine, University of Florida College of Medicine - Jacksonville, Jacksonville, USA.

出版信息

Cureus. 2022 May 25;14(5):e25332. doi: 10.7759/cureus.25332. eCollection 2022 May.

Abstract

Chronic inflammatory demyelinating polyneuropathy (CIDP) is a neurological disorder of the peripheral nerves which can lead to gradually increasing motor and sensory loss. It can be a difficult entity to diagnose, particularly in elderly patients with a history of Diabetes Mellitus due to their overlapping neuropathic syndromes. Reported is a case of CIDP in an elderly female who manifested multiple sensory, motor, and autonomic complaints. A compilation of clinical features, neuroimaging, lumbar puncture, electromyography, nerve conduction studies, and nerve biopsy were used to reach the diagnosis. Highlighted is a clinical approach to identifying CIDP that can cause neuropathy in the setting of other potential confounding disorders namely Diabetes Mellitus.

摘要

慢性炎症性脱髓鞘性多发性神经病(CIDP)是一种周围神经的神经疾病,可导致运动和感觉功能逐渐丧失。它可能是一种难以诊断的疾病,特别是在有糖尿病病史的老年患者中,因为他们的神经病变综合征相互重叠。本文报告一例老年女性CIDP病例,该患者表现出多种感觉、运动和自主神经症状。综合临床特征、神经影像学、腰椎穿刺、肌电图、神经传导研究和神经活检以做出诊断。重点介绍了一种在存在其他潜在混杂疾病(即糖尿病)的情况下识别可导致神经病变的CIDP的临床方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b9e9/9236626/27c6e5a24478/cureus-0014-00000025332-i01.jpg

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