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糖尿病:如何管理2型糖尿病患者的超重和肥胖问题。

Diabetes: how to manage overweight and obesity in type 2 diabetes mellitus.

作者信息

Wesling Megan, D'Souza Jennifer J

机构信息

HSC College of Pharmacy, University of North Texas Health Science Center at Fort Worth, Fort Worth, TX, USA.

Midwestern University, Downers Grove, IL, USA.

出版信息

Drugs Context. 2022 Jun 14;11. doi: 10.7573/dic.2021-11-7. eCollection 2022.

DOI:10.7573/dic.2021-11-7
PMID:35775076
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9205573/
Abstract

The prevalence of obesity worldwide continues to increase substantially. Obesity is a chronic disease that can lead to other health conditions, including type 2 diabetes mellitus (T2DM). A variety of treatment options are available to treat T2DM. With its prevalence increasing, it is essential that healthcare professionals assess how their patients' current diabetes treatment is being managed to avoid further weight gain in those with overweight or obesity.

摘要

全球肥胖症的患病率持续大幅上升。肥胖是一种慢性疾病,可导致包括2型糖尿病(T2DM)在内的其他健康问题。治疗T2DM有多种选择。随着其患病率的增加,医疗保健专业人员必须评估其患者当前的糖尿病治疗管理情况,以避免超重或肥胖患者进一步体重增加。

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2
Efficacy and Safety of Dulaglutide 3.0 mg and 4.5 mg Versus Dulaglutide 1.5 mg in Metformin-Treated Patients With Type 2 Diabetes in a Randomized Controlled Trial (AWARD-11).在一项随机对照试验(AWARD-11)中,接受二甲双胍治疗的 2 型糖尿病患者使用 3.0mg 和 4.5mg 度拉鲁肽与 1.5mg 度拉鲁肽的疗效和安全性。
Diabetes Care. 2021 Mar;44(3):765-773. doi: 10.2337/dc20-1473. Epub 2021 Jan 4.
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Acarbose With Comparable Glucose-Lowering but Superior Weight-Loss Efficacy to Dipeptidyl Peptidase-4 Inhibitors: A Systematic Review and Network Meta-Analysis of Randomized Controlled Trials.阿卡波糖具有与二肽基肽酶-4 抑制剂相当的降血糖效果,但减重效果更优:一项随机对照试验的系统评价和网络荟萃分析。
Front Endocrinol (Lausanne). 2020 Jun 5;11:288. doi: 10.3389/fendo.2020.00288. eCollection 2020.
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Effects of Dapagliflozin on Epicardial Fat Thickness in Patients with Type 2 Diabetes and Obesity.达格列净对 2 型糖尿病合并肥胖患者心外膜脂肪厚度的影响。
Obesity (Silver Spring). 2020 Jun;28(6):1068-1074. doi: 10.1002/oby.22798. Epub 2020 Apr 30.
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J Clin Endocrinol Metab. 2020 Jul 1;105(7). doi: 10.1210/clinem/dgaa204.
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Oral Semaglutide: First-in-Class Oral GLP-1 Receptor Agonist for the Treatment of Type 2 Diabetes Mellitus.口服司美格鲁肽:用于治疗 2 型糖尿病的首个口服 GLP-1 受体激动剂。
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