艾滋病相关组织胞浆菌病和内脏利什曼病继发噬血细胞性淋巴组织细胞增生症。
Hemophagocytic lymphohistiocytosis secondary to AIDS-related histoplasmosis and visceral leishmaniasis.
机构信息
Infectious Diseases Division, 62916Hospital Juan A. Fernández, Ciudad Autónoma de Buenos Aires, Argentina.
Microbiology Section, 62916Hospital Juan A. Fernández, Ciudad Autónoma de Buenos Aires, Argentina.
出版信息
Int J STD AIDS. 2022 Aug;33(9):873-876. doi: 10.1177/09564624221110986. Epub 2022 Jul 1.
Hemophagocytic Lymphohistiocytosis (HLH) is a rare, highly aggressive syndrome involving dysregulated immune response. Most cases are secondary to underlying diseases including infections, autoimmune disorders and malignancies. The burden of disease of histoplasmosis and leishmaniosis associated with advanced HIV is still significant in low-and-middle income countries (LMIC). We present a case of histoplasmosis and leishmaniasis associated HLH in a man with an AIDS diagnosis.
噬血细胞性淋巴组织细胞增生症（HLH）是一种罕见的、侵袭性很强的综合征，涉及免疫反应失调。大多数病例继发于潜在疾病，包括感染、自身免疫性疾病和恶性肿瘤。在中低收入国家（LMIC），与晚期 HIV 相关的组织胞浆菌病和利什曼病的疾病负担仍然很大。我们报告了一例 AIDS 诊断患者合并组织胞浆菌病和利什曼病相关 HLH 的病例。
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