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Acta Biomed. 2022 Jul 1;93(3):e2022086. doi: 10.23750/abm.v93i3.12576.
Papillary thyroid carcinoma accounts for 85% of thyroid follicular epithelial-derived cancers. The identification of pathogenetic mechanisms improved the understating of papillary thyroid carcinoma pathogenesis. The current study aims to examine the research productivity and trends in the genetics of papillary thyroid carcinoma from 1991 to 2020.
The Web of Science Core Collection database was searched to retrieve the relevant literature. A search string was applied and 1,741 relevant records were selected for the analysis. Bibliometric techniques were used in the statistical analysis with the help of Biblioshiny (RStudio).
The growth in the number of publications was observed to be over a hundred publications per year since 2015. 'Thyroid' published the highest number of publications, followed by 'Journal of Clinical Endocrinology & Metabolism'. 'Nikiforov YE' was identified as the most productive researcher with a total of 49 publications. Out of the top 20 most contributing researchers, seven belonged to Italy, and four were from the USA. 'University of Pittsburgh' contributed the highest number of publications. The top contributing countries in this field were the USA, China, and Italy. BRAF and RAS were among the frequently used keywords.
This bibliometric review demonstrates that investigating the genetics underlying papillary thyroid carcinoma is a rapidly growing area of research. During the last two decades, China has been a significant contributor to the field. Besides, institutions in USA and Italy have significantly contributed to research in the genetics of papillary thyroid carcinoma. (www.actabiomedica.it).
甲状腺乳头状癌占甲状腺滤泡上皮来源癌的 85%。对发病机制的认识提高了对甲状腺乳头状癌发病机制的理解。本研究旨在检查 1991 年至 2020 年间甲状腺乳头状癌遗传学的研究生产力和趋势。
在 Web of Science 核心合集数据库中搜索相关文献。应用搜索字符串，选择了 1741 篇相关记录进行分析。在 Biblioshiny（RStudio）的帮助下，使用文献计量学技术进行统计分析。
自 2015 年以来，每年发表的论文数量增长超过 100 篇。“甲状腺”发表的论文数量最多，其次是“临床内分泌代谢杂志”。“Nikiforov YE”被确定为最具生产力的研究人员，共发表了 49 篇论文。在排名前 20 的研究人员中，有 7 人来自意大利，4 人来自美国。“匹兹堡大学”发表的论文数量最多。该领域贡献最多的国家是美国、中国和意大利。BRAF 和 RAS 是常用的关键词之一。
这项文献计量学综述表明，研究导致甲状腺乳头状癌的遗传学是一个快速发展的研究领域。在过去的二十年中，中国一直是该领域的重要贡献者。此外，美国和意大利的机构也为甲状腺乳头状癌的遗传学研究做出了重大贡献。
