Rajendran Pragadeshwaran, Karim Habib Reazaul, Singh Vikramjit, Bais Shruti
Department of Anaesthesiology, Critical Care and Pain Medicine. All India Institute of Medical Sciences, Raipur. India.
Turk J Anaesthesiol Reanim. 2022 Jun;50(Supp1):S71-S73. doi: 10.5152/TJAR.2021.21422.
Unlike neuroblastoma, ganglioneuroma is a rare entity in children younger than 7 years of age. Further, these tumors are mostly inactive endocrinologically with the symptoms of abdominal pain or palpable mass. Unfortunately, when functional, they mimic or occasionally coexist with pheochromocytoma. While perioperative management of pheochromocytoma has evolved, very little is known regarding the periopera- tive management of functioning ganglioneuroma. Hormone secretion due to surgical manipulation and anaesthesia leads to life-threatening complications. The risk further increases when associated with other congenital comorbidities. Furthermore, the corona pandemic, in other words, coronavirus disease 2019 infection, in the perioperative period is another new challenge. We report perioperative management and outcome of a functioning retroperitoneal ganglioneuroma in a 2-year-old child, having a ventricular septal defect, spina bifida occulta, and coronavirus disease 2019. The case also highlights decision-making challenges during the coronavirus disease 2019 pandemic.
与神经母细胞瘤不同,神经节神经瘤在7岁以下儿童中是一种罕见的疾病。此外,这些肿瘤大多在内分泌方面无活性,表现为腹痛或可触及肿块的症状。不幸的是,当它们具有功能性时,会模仿嗜铬细胞瘤,或偶尔与之共存。虽然嗜铬细胞瘤的围手术期管理已经有所发展,但关于功能性神经节神经瘤的围手术期管理却知之甚少。手术操作和麻醉引起的激素分泌会导致危及生命的并发症。当与其他先天性合并症相关时,风险会进一步增加。此外,在围手术期发生的新冠疫情,即2019冠状病毒病感染,是另一个新的挑战。我们报告了一名2岁患有室间隔缺损、隐性脊柱裂和2019冠状病毒病的儿童,其功能性腹膜后神经节神经瘤的围手术期管理及结果。该病例还凸显了2019冠状病毒病大流行期间的决策挑战。