Anesthesiology and Reanimation Department, Ankara City Hospital, Health Sciences University, Bilkent Blvd. No:1, 66800, Ankara/Çankaya, Turkey.
Anesthesiology and Reanimation Department, Ankara Ataturk Sanatoryum Training and Research Hospital, Ankara, Turkey.
Ir J Med Sci. 2023 Jun;192(3):1321-1325. doi: 10.1007/s11845-022-03079-7. Epub 2022 Jul 1.
We aimed to evaluate and compare the efficacy and complications of three consecutive prone positions (PP) in COVID-19 ICU.
Patients with ARDS and placed in PP for 3 times (PP1, PP2, PP3) consecutively were included. Arterial blood gases (ABG), partial pressure of arterial oxygen/fraction of inspired oxygen (PaO/FiO) ratios, partial pressure of carbondioxide (PaCO), PEEP, and FiO were recorded before (bPP), during (dPP), and after (aPP) every prone positioning. Eye, skin, nerve, and tube complications related to PP were collected.
In all positions, PaO value during PP was significantly higher than PaO before and after prone position (p = 0.001). PaO values were similar in all (PP1, PP2, PP3) bPP arterial blood gases. We found difference in PaO values during prone position between the first (PP1) and second proning (PP2). When each prone was evaluated within itself, PaO/FiO increases after proning compared to before proning. PaO/FiO during PP were higher compared to before proning ones. PaO/FiO during PP1 was significantly higher compared to during PP3 (p = 0.005). In PP3, PEEP values bPP, dPP, and aPP were significantly higher than PEEP values after the second prone (p = 0.02, p = 0.001, p = 0.01). In the third prone, PaCO levels were higher than in PP1 and PP2. There were eye complications in 13, tube-related complications in 10, skin complications in 30, and nerve damage in 1 patient.
We believe that a more careful decision should be made after the second prone position in patients who have to be placed in sequential prone position.
我们旨在评估和比较 COVID-19 ICU 中连续 3 次俯卧位(PP)的疗效和并发症。
纳入连续 3 次(PP1、PP2、PP3)俯卧位的 ARDS 患者。记录动脉血气(ABG)、动脉血氧分压/吸入氧分数(PaO/FiO)比值、二氧化碳分压(PaCO)、PEEP 和 FiO 在俯卧位前(bPP)、期间(dPP)和之后(aPP)的值。收集与 PP 相关的眼部、皮肤、神经和导管并发症。
所有体位下,PP 期间的 PaO 值均显著高于俯卧位前和后(p=0.001)。所有(PP1、PP2、PP3)bPP 动脉血气中的 PaO 值均相似。我们发现首次(PP1)和第二次俯卧位(PP2)期间的 PaO 值存在差异。当单独评估每次俯卧位时,俯卧位后 PaO/FiO 比俯卧位前增加。PP 期间的 PaO/FiO 高于俯卧位前。PP1 期间的 PaO/FiO 明显高于 PP3 期间(p=0.005)。在 PP3 中,PP 前、中、后的 PEEP 值均显著高于第二次俯卧位后(p=0.02、p=0.001、p=0.01)。在第三次俯卧位中,PaCO 水平高于 PP1 和 PP2。有 13 例发生眼部并发症,10 例发生导管相关并发症,30 例发生皮肤并发症,1 例发生神经损伤。
我们认为,对于必须连续俯卧位的患者,在第二次俯卧位后应更谨慎地做出决策。