Suppr超能文献

COVID-19 重症监护病房连续俯卧位治疗的效果和并发症评估:一项回顾性研究。

Evaluation of the efficiency and complications of the consecutive proning in COVID-19 ICU: a retrospective study.

机构信息

Anesthesiology and Reanimation Department, Ankara City Hospital, Health Sciences University, Bilkent Blvd. No:1, 66800, Ankara/Çankaya, Turkey.

Anesthesiology and Reanimation Department, Ankara Ataturk Sanatoryum Training and Research Hospital, Ankara, Turkey.

出版信息

Ir J Med Sci. 2023 Jun;192(3):1321-1325. doi: 10.1007/s11845-022-03079-7. Epub 2022 Jul 1.

Abstract

PURPOSE

We aimed to evaluate and compare the efficacy and complications of three consecutive prone positions (PP) in COVID-19 ICU.

MATERIALS AND METHOD

Patients with ARDS and placed in PP for 3 times (PP1, PP2, PP3) consecutively were included. Arterial blood gases (ABG), partial pressure of arterial oxygen/fraction of inspired oxygen (PaO/FiO) ratios, partial pressure of carbondioxide (PaCO), PEEP, and FiO were recorded before (bPP), during (dPP), and after (aPP) every prone positioning. Eye, skin, nerve, and tube complications related to PP were collected.

RESULTS

In all positions, PaO value during PP was significantly higher than PaO before and after prone position (p = 0.001). PaO values were similar in all (PP1, PP2, PP3) bPP arterial blood gases. We found difference in PaO values during prone position between the first (PP1) and second proning (PP2). When each prone was evaluated within itself, PaO/FiO increases after proning compared to before proning. PaO/FiO during PP were higher compared to before proning ones. PaO/FiO during PP1 was significantly higher compared to during PP3 (p = 0.005). In PP3, PEEP values bPP, dPP, and aPP were significantly higher than PEEP values after the second prone (p = 0.02, p = 0.001, p = 0.01). In the third prone, PaCO levels were higher than in PP1 and PP2. There were eye complications in 13, tube-related complications in 10, skin complications in 30, and nerve damage in 1 patient.

CONCLUSION

We believe that a more careful decision should be made after the second prone position in patients who have to be placed in sequential prone position.

摘要

目的

我们旨在评估和比较 COVID-19 ICU 中连续 3 次俯卧位(PP)的疗效和并发症。

材料和方法

纳入连续 3 次(PP1、PP2、PP3)俯卧位的 ARDS 患者。记录动脉血气(ABG)、动脉血氧分压/吸入氧分数(PaO/FiO)比值、二氧化碳分压(PaCO)、PEEP 和 FiO 在俯卧位前(bPP)、期间(dPP)和之后(aPP)的值。收集与 PP 相关的眼部、皮肤、神经和导管并发症。

结果

所有体位下,PP 期间的 PaO 值均显著高于俯卧位前和后(p=0.001)。所有(PP1、PP2、PP3)bPP 动脉血气中的 PaO 值均相似。我们发现首次(PP1)和第二次俯卧位(PP2)期间的 PaO 值存在差异。当单独评估每次俯卧位时,俯卧位后 PaO/FiO 比俯卧位前增加。PP 期间的 PaO/FiO 高于俯卧位前。PP1 期间的 PaO/FiO 明显高于 PP3 期间(p=0.005)。在 PP3 中,PP 前、中、后的 PEEP 值均显著高于第二次俯卧位后(p=0.02、p=0.001、p=0.01)。在第三次俯卧位中,PaCO 水平高于 PP1 和 PP2。有 13 例发生眼部并发症,10 例发生导管相关并发症,30 例发生皮肤并发症,1 例发生神经损伤。

结论

我们认为,对于必须连续俯卧位的患者,在第二次俯卧位后应更谨慎地做出决策。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验