Department of Health Care Services, Program in Geriatric Care, Yunus Emre Vocational School, Anadolu University, Tepebasi, 26470, Eskisehir, Turkey.
Faculty of Physical Therapy and Rehabilitation, Hacettepe University, Ankara, Turkey.
Acta Neurol Belg. 2023 Jun;123(3):865-872. doi: 10.1007/s13760-022-02007-x. Epub 2022 Jul 1.
Loss of automaticity and deteriorated executive function give rise to dual task deficits in Parkinson's disease (PD). This study aimed to compare single task and dual task upper and lower extremity skills in people with PD (PwPD) at different stages of PD and to examine the dual task effect (DTE) on upper and lower extremity skills in PwPD at different stages of PD. The second aim was to investigate the relationship between the DTE and the quality of life in PwPD.
30 patients divided into 2 groups as mild PD group and moderate PD group according to the Modified Hoehn & Yahr Scale. 15 age matched healthy adults were recruited as the control group. The Unified Parkinson's Disease Rating Scale (UPDRS), the Purdue Pegboard Test (PPT), the Timed Up and Go Test (TUG), the 10 Meter Walk Test (10MWT), and the Parkinson's Disease Questionnaire (PDQ-8) were used for assessments.
Single task and dual task scores of all assessments of all groups were significantly different. The DTE on PPT was greater in mild and moderate PD groups than control group and significantly lower in mild PD group than moderate PD group. However, DTE on the TUG and 10MWT was not different in mild PD group than control group and DTE significantly lower in both groups than moderate PD group. Significant correlations between the DTE on PPT, TUG and 10MWT and the PDQ-8 in PwPD were observed.
Dual task has a worsening effect on upper and lower extremity skills in PwPD. This effect can be observed earlier in upper extremity skills than lower extremity skills. Also, the DTE and the QoL in PwPD are related.
帕金森病（PD）患者的自主性丧失和执行功能恶化导致双重任务缺陷。本研究旨在比较不同 PD 阶段患者的单任务和双重任务上肢和下肢技能，并研究 PD 不同阶段患者双重任务效应（DTE）对上肢和下肢技能的影响。第二个目的是研究 DTE 与 PD 患者生活质量之间的关系。
根据改良 Hoehn & Yahr 量表，将 30 名患者分为轻度 PD 组和中度 PD 组。招募了 15 名年龄匹配的健康成年人作为对照组。采用统一帕金森病评定量表（UPDRS）、普渡钉板测试（PPT）、计时起立行走测试（TUG）、10 米步行测试（10MWT）和帕金森病问卷（PDQ-8）进行评估。
所有组的所有评估的单任务和双重任务评分均有显著差异。与对照组相比，轻度和中度 PD 组的 PPT 双重任务评分更高，且轻度 PD 组的评分明显低于中度 PD 组。然而，TUG 和 10MWT 的 DTE 在轻度 PD 组与对照组之间无差异，且两组的 DTE 均明显低于中度 PD 组。在 PD 患者中，PPT、TUG 和 10MWT 的 DTE 与 PDQ-8 之间存在显著相关性。
双重任务对上肢和下肢技能的影响在 PD 患者中更为明显。这种影响在上肢技能中比在下肢技能中更早观察到。此外，DTE 和 PD 患者的 QoL 相关。
