Clinic for Otorhinolaryngology and Maxillofacial Surgery, Clinical Center of Serbia, Belgrade, Serbia.
Medical Faculty, University of Belgrade, Belgrade, Serbia.
PLoS One. 2022 Jul 1;17(7):e0270793. doi: 10.1371/journal.pone.0270793. eCollection 2022.
Persistent symptoms of chronic otitis media cause limitations in daily routine and social interactions, influencing significantly patients' quality of life and mental health. The purpose of the study was to assess the intensity depression, anxiety and stress symptoms in patients with chronic otitis media and to examine if patient demographic data, characteristics and reported symptoms of otitis influence reported depression, anxiety and stress symptoms.
The study included 316 adult patients diagnosed with unilateral or bilateral chronic otitis media with or without cholesteatoma. Patients underwent a complete otological, audiological and radiological assessment. Chronic otitis media questionnaire 12 (COMQ-12) was used to assess the impact of COM and Depression Anxiety Stress Scale 21 (DASS-21) was used for depression, anxiety and stress assessment.
Some level of anxiety and stress were detected in 70.57% 49.37% of the patients, respectively. 13.29% of the patients had scores indicating depression disorder. The mean value of the COMQ-12 questionnaire for this group of patients was 26.24 (SD±11.47) More intense symptoms of COM were significantly associated (p<0.05) with higher scores on DASS-21 subscales. Multivariate logistic regression analysis indicated that significant positive predictors of higher anxiety scores were pure tone average (PTA) on better and worse hearing ear (p<0.05). Drainage from the ear, hearing problems at home and tinnitus were significant positive predictors of a higher DASS-depression score. (p<0.05).
The study confirmed positive correlation between reported level of anxiety, depression and stress, severity of COM symptoms and quality of life. Level of hearing on the better and worse hearing ear were significant positive predictors of anxiety and stress in patients with COM.
慢性中耳炎的持续症状会限制日常生活和社交互动，显著影响患者的生活质量和心理健康。本研究旨在评估慢性中耳炎患者抑郁、焦虑和压力症状的强度，并探讨患者的人口统计学数据、特征和报告的中耳炎症状是否会影响报告的抑郁、焦虑和压力症状。
该研究纳入了 316 名被诊断为单侧或双侧慢性中耳炎伴或不伴胆脂瘤的成年患者。患者接受了全面的耳鼻喉科、听力和影像学评估。使用慢性中耳炎问卷 12 项（COMQ-12）评估 COM 的影响，使用抑郁、焦虑和压力量表 21 项（DASS-21）评估抑郁、焦虑和压力。
分别有 70.57%和 49.37%的患者存在一定程度的焦虑和压力。13.29%的患者存在抑郁障碍评分。该组患者的 COMQ-12 问卷平均得分（SD±11.47）为 26.24。COM 症状更严重与 DASS-21 子量表得分更高显著相关（p<0.05）。多变量逻辑回归分析表明，更好和更差听力耳的纯音平均（PTA）是焦虑评分较高的显著正预测因子（p<0.05）。耳内引流、家庭听力问题和耳鸣是 DASS-抑郁评分较高的显著正预测因子（p<0.05）。
本研究证实了报告的焦虑、抑郁和压力水平、COM 症状严重程度和生活质量之间存在正相关。更好和更差听力耳的听力水平是 COM 患者焦虑和压力的显著正预测因子。
