Department of Microbiology and Instituto de Investigación Biosanitaria Ibs.GRANADA, University Hospital Virgen de las Nieves, Granada, Spain.
Department of Microbiology and Instituto de Investigación Biosanitaria Ibs.GRANADA, University Hospital Virgen de las Nieves, Granada, Spain.
Anaerobe. 2022 Aug;76:102608. doi: 10.1016/j.anaerobe.2022.102608. Epub 2022 Jun 28.
To report a series of four uncommon cases of bacteremia due to Parabacteroides distasonis.
We have analyzed the epidemiological characteristics, clinical features, diagnostic methods, treatment and outcome of these patients.
Two sets of blood cultures of each patient yielded a pure culture of an anaerobic microorganism identified as P. distasonis by MALDI-TOF MS, and confirmed by 16S rRNA gene sequencing. All patients were male and they had risk factors for anaerobic bacteremia. All isolates were susceptible to metronidazole and the outcome was successful in three patients.
Bloodstream infections due to P. distasonis are still rare. MALDI-TOF MS appear to be an excellent tool for the correct identification.
报告 4 例罕见的拟杆菌属 distasonis 菌血症病例。
我们分析了这些患者的流行病学特征、临床特征、诊断方法、治疗和转归。
每位患者的 2 套血培养均获得纯培养的厌氧微生物，MALDI-TOF MS 鉴定为拟杆菌属 distasonis，16S rRNA 基因测序进一步证实。所有患者均为男性，存在厌氧细菌血症的危险因素。所有分离株均对甲硝唑敏感，3 例患者的治疗结局成功。
拟杆菌属 distasonis 引起的血流感染仍然罕见。MALDI-TOF MS 似乎是正确鉴定的极好工具。
