Institut de Biologie des Hôpitaux de Nantes, Service de Bactériologie Et Des Contrôles Microbiologiques, CHU Nantes, Nantes Université, 9 Quai Moncousu, 44093, Cedex 01, Nantes, France.
Nantes Study Group Members of CRIOGO (Centre de Référence Des Infections Ostéo-Articulaires du Grand Ouest), Nantes, France.
Eur J Clin Microbiol Infect Dis. 2024 Feb;43(2):395-399. doi: 10.1007/s10096-023-04731-5. Epub 2023 Dec 14.
We report two uncommon cases of osteosynthetic cervical spine infection. Clinical patient features, microbiological strain characteristics, diagnostic methods, and treatment were analyzed. Both patients were male, and one had risk factors for surgical site infection. During surgery, perioperative samples were positive yielding an anaerobic microorganism identified as Cutibacterium namnetense by MALDI-TOF MS and confirmed by 16S rRNA/gyrB genes sequencing. All isolates were fully susceptible. C. namnetense osteosynthetic cervical spine infections are rare. Both cases were early surgical site infections. Bruker MALDI-TOF MS appears to be an excellent tool for rapid and accurate identification. Amoxicillin seems to be an option for the treatment.
我们报告了两例罕见的颈椎骨合成感染病例。分析了临床患者特征、微生物株特征、诊断方法和治疗方法。两名患者均为男性，其中一名有手术部位感染的危险因素。手术期间，围手术期样本呈阳性，通过 MALDI-TOF MS 鉴定为一种厌氧微生物，命名为 Cutibacterium namnetense，并通过 16S rRNA/gyrB 基因测序得到确认。所有分离株均完全敏感。C. namnetense 颈椎骨合成感染较为罕见。这两个病例都是早期手术部位感染。布鲁克 MALDI-TOF MS 似乎是一种快速准确鉴定的极好工具。阿莫西林似乎是一种治疗选择。
