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与……亚历山大·沃洛达尔斯基的开放式对话。

An open chat with…Alexander Wlodawer.

机构信息

FEBS Open Bio Editorial Office, Cambridge, UK.

Center for Structural Biology, National Cancer Institute, Frederick, MD, USA.

出版信息

FEBS Open Bio. 2022 Sep;12(9):1564-1566. doi: 10.1002/2211-5463.13462. Epub 2022 Jul 7.

DOI:10.1002/2211-5463.13462
PMID:35778923
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9433821/
Abstract

Alexander Wlodawer has been a member of the FEBS Open Bio Editorial Board since the journal's launch in 2011. Currently, he is Senior Investigator at the Center for Structural Biology, National Cancer Institute in Frederick, Maryland, USA. He received his Ph.D. from the University of California, Los Angeles in 1974, completed postdoctoral training at Stanford University and has also worked at the National Bureau of Standards, the ABL-Basic Research Program at the NCI-FCRDC and the University of Cambridge, UK. He is Doctor Honoris Causa of the Technical University of Lodz, Poland. Alexander Wlodawer is also a recipient of the 2006 NCI Mentor of Merit Award, was awarded the Heyrovsky Honorary Medal by the Czech Academy of Sciences in 2008, was elected Foreign Member of the Polish Academy of Sciences in 2005, and has been member of the Editorial Board of The FEBS Journal since 2007. He is currently Editor-in-Chief of the journal Current Research in Structural Biology. In this compelling interview, he shares with us his experiences on solving the structures of IL-4 and retroviral proteases, advice on how to deal with being scooped, and his thoughts on open data sharing and AlphaFold.

摘要

亚历山大·沃洛达沃(Alexander Wlodawer)自 2011 年该期刊创刊以来一直担任 FEBS Open Bio 编辑委员会成员。他现任美国马里兰州弗雷德里克市美国国立癌症研究所结构生物学中心高级研究员。他于 1974 年获得加利福尼亚大学洛杉矶分校博士学位,在斯坦福大学完成博士后培训,曾就职于美国国家标准局、NCI-FCRDC ABL 基础研究计划和英国剑桥大学。他是波兰罗兹技术大学的荣誉博士。亚历山大·沃洛达沃还获得了 2006 年 NCI 卓越导师奖,2008 年获得捷克科学院海洛夫斯基纪念奖章,2005 年当选为波兰科学院外籍院士,并自 2007 年起担任 FEBS 杂志编辑委员会成员。他现任期刊 Current Research in Structural Biology 的主编。在这次引人入胜的采访中,他与我们分享了他在解决 IL-4 和逆转录病毒蛋白酶结构方面的经验、应对被抢先的建议,以及他对开放数据共享和 AlphaFold 的看法。

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