VA Connecticut Healthcare System, West Haven, CT, United States of America; Department of Psychiatry, Yale University School of Medicine, New Haven, CT, United States of America.
Olin Neuropsychiatry Research Center, Hartford Healthcare Behavioral Health Network, Hartford, CT, United States of America.
Schizophr Res. 2022 Aug;246:165-171. doi: 10.1016/j.schres.2022.06.015. Epub 2022 Jun 29.
While there is increasing support for the efficacy of psychosocial interventions for people with SMI, the real-world effectiveness of such treatments is diminished by lack of motivation for treatment, leading to poor treatment engagement/dropout. We sought to evaluate the efficacy of motivational interviewing (MI) in improving attendance in a full course of cognitive training, examine motivation level as a potential mechanism of action, and examine variables associated with initial engagement in the training.
One hundred fourteen participants with SMI were randomized to MI or sham control interview (CI), both of which were followed by a 4-month active phase during which participants could attend up to 50 unpaid cognitive training sessions.
Fidelity to the MI intervention was high, and MI condition was associated with increases in perceived value of training tasks and, to a lesser extent, how enjoyable/interesting they were rated. Twenty-nine percent of the full sample did not attend any training sessions. In ITT analyses, there was no significant between-group impact of MI on treatment attendance, though one emerged when participants who did not attend any sessions were excluded. Treatment attendance was predicted by the level of motivation achieved after the MI/CI intervention. Those who attended at least one training session (regardless of randomization) were more likely to believe they had cognitive impairments, had higher IQ and had less severe general psychiatric symptoms.
MI showed some promise and may be a worthwhile addition to more comprehensive, robust efforts to promote initial treatment engagement and subsequent adherence.
虽然越来越多的人支持对精神障碍患者进行心理社会干预的疗效,但由于缺乏治疗动机,导致治疗参与度/脱落率低,这些治疗在现实世界中的效果受到了影响。我们试图评估动机性访谈(MI)在提高认知训练全程参与度方面的效果,检验动机水平作为一种潜在的作用机制,并检验与初始训练参与度相关的变量。
114 名精神障碍患者被随机分配到 MI 或假对照访谈(CI)组,两组均随后进行为期 4 个月的积极治疗阶段,在此期间,参与者最多可参加 50 次免费认知训练课程。
MI 干预的忠实度很高,MI 组对训练任务的感知价值以及对训练的享受/趣味性的评价均有所增加。样本中 29%的人没有参加任何培训课程。在 ITT 分析中,MI 对治疗参与度没有显著的组间影响,但当排除未参加任何课程的参与者时,就会出现这种影响。治疗参与度由 MI/CI 干预后达到的动机水平预测。那些至少参加了一次培训课程的人(无论随机分组如何)更有可能认为自己有认知障碍,智商更高,一般精神病症状更轻。
MI 显示出了一定的前景,可能是促进初始治疗参与度和后续依从性的更全面、更有力的努力的有益补充。