Yamada T, Murayama T, Taguchi H
Hinyokika Kiyo. 1987 Jan;33(1):85-9.
The patient was a 46-year-old man. His chief complaints were urinary frequency and pain on urination. They first appeared one year earlier. The patient had had a history of bronchial asthma and urticaria. Vesical capacity decreased and vesico-cutaneous developed. The urine sediment contained eosinophils and vesico ureteral reflux was observed. The bladder tissues contained a moderate amount of eosinophils, lymphocytes and plasma cells. The total IgE was 360 IU/ml. The IgE RAST score and immediate reaction to the skin tests were all negative. The Arthus and delayed-type reaction skin tests were positive to various Eumycetees and foods. Provocation tests by eating foods such as eggs, meats, and shellfish reproduced the above-mentioned bladder disorders. The patient was therefore put on a diet that restricted the amount of animal protein consumed except for white meat fishes, and a mast cell membrane stabilizer was administered. The interstitial cystitis improved but the asthma aggravated. The cystitis was found to develop alternately with asthma.
患者为一名46岁男性。他的主要症状是尿频和排尿疼痛，这些症状于一年前首次出现。该患者有支气管哮喘和荨麻疹病史。膀胱容量减小且出现膀胱皮肤瘘。尿沉渣中含有嗜酸性粒细胞，并观察到膀胱输尿管反流。膀胱组织含有中等数量的嗜酸性粒细胞、淋巴细胞和浆细胞。总IgE为360 IU/ml。IgE RAST评分和皮肤试验的即刻反应均为阴性。Arthus反应和迟发型反应皮肤试验对各种真菌和食物呈阳性。食用鸡蛋、肉类和贝类等食物进行激发试验再现了上述膀胱疾病。因此，患者采用了一种饮食方案，除白肉鱼外限制动物蛋白的摄入量，并给予肥大细胞膜稳定剂。间质性膀胱炎有所改善，但哮喘加重。发现膀胱炎与哮喘交替发作。
