Dr Rafia Afrose, Assistant Professor, Department of Medicine, Dhaka Medical College, Dhaka,, Bangladesh; E-mail:
Mymensingh Med J. 2022 Jul;31(3):749-757.
The National Tuberculosis Control Program (NTP) is one of the largest programs run by the state with many successes. However, underreporting is considered a real flaw of the current program. To report the characteristics and outcomes of TB patients registered in an upazila health complex in Kazipur, Sirajganj district, Bangladesh between September 2018 and February 2019 under the control of NTP was the objective of the study. This retrospective cohort study was conducted using routinely collected program data from the aforementioned site. Data retrieved from the hospital record form. Formal permission was obtained from the local authority. Consent statements and ethical aspects were waived due to the retrospective nature of the study. Analysis was performed using SPSS 20.0. A total of 207 tuberculosis cases were included with an average age of presentation of 43 years. Approximately 82.0% had pulmonary tuberculosis (PTB) and the rest had extrapulmonary tuberculosis (EPTB). PTB was more common in males, whereas EPTB was common in females (p=0.01). Of all cases, 84.0% were diagnosed by a positive sputum smear and 16.0% were diagnosed clinically with a negative sputum smear. Attendance at follow-up was 82.12%, 70.04% and 68.59% at months 2, 5 and 6 following index admission respectively. Overall, the cure rate was higher in PTB than EPTB [146 (85.9%) vs. 5 (13.5%), p<0.001). The rate of treatment completion was 25.1% (n=52) and the death count was 1.4% (n=3) [PTB-1.2 (n=2) vs. EPTB-2.7% (n=1)]. A gradual decline in reporting or completion of treatment was observed in this setting. However, a nationwide study is warranted to explore this issue in detail.
国家结核病控制规划（NTP）是国家运行的最大项目之一，取得了许多成功。然而，漏报被认为是当前项目的一个真正缺陷。本研究旨在报告孟加拉国锡拉杰甘杰区卡齐普尔的一个分区卫生综合体中，2018 年 9 月至 2019 年 2 月期间在 NTP 控制下登记的结核患者的特征和结局。这项回顾性队列研究使用来自上述地点的常规收集的项目数据进行。数据从医院记录表格中检索。由于研究的回顾性性质，从当地当局获得了正式许可。由于研究的回顾性性质，放弃了同意声明和伦理方面的考虑。使用 SPSS 20.0 进行分析。共纳入 207 例结核病病例，平均发病年龄为 43 岁。大约 82.0%的患者患有肺结核（PTB），其余的患者患有肺外结核（EPTB）。PTB 在男性中更为常见，而 EPTB 在女性中更为常见（p=0.01）。所有病例中，84.0%通过痰涂片阳性诊断，16.0%通过痰涂片阴性临床诊断。在索引入院后第 2、5 和 6 个月的随访中，出席率分别为 82.12%、70.04%和 68.59%。总体而言，PTB 的治愈率高于 EPTB[146（85.9%）比 5（13.5%），p<0.001]。完成治疗的比例为 25.1%（n=52），死亡人数为 1.4%（n=3）[PTB-1.2（n=2）比 EPTB-2.7%（n=1）]。在这种情况下，报告或完成治疗的比例逐渐下降。然而，需要进行全国性研究来详细探讨这个问题。
